Evidence map›Paper›PMID 42743590›Full record

Trial reportJournal of medical Internet research2026

The Impact of Chatbot Type and Normative Messaging on Chatbot Usage Intention Based on the Health Technology Acceptance Model: Randomized Controlled Trial.

Yi Liao, Anne Madeo, Caitlin G Allen, Melissa K Frey, Whitney Maxwell, Chelsey Schlechter, Ravi N Sharaf, Kensaku Kawamoto, Guilherme Del Fiol, Kimberly A Kaphingst

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of medical Internet research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yi LiaoDepartment of Communication, University of Utah, 255 S Central Campus Dr, Salt Lake City, UT, 84112, United States, 1 801-581-6889.ORCID http://orcid.org/0000-0003-4654-9739
Anne MadeoHuntsman Cancer Institute, Salt Lake City, UT, United States.ORCID http://orcid.org/0000-0003-2048-9491
Caitlin G AllenSchool of Medicine, Wake Forest University, Winston-Salem, NC, United States.ORCID http://orcid.org/0000-0002-6288-3529
Melissa K FreyWeill Cornell Medicine, New York City, NY, United States.ORCID http://orcid.org/0000-0002-6705-1211
Whitney MaxwellHuntsman Cancer Institute, Salt Lake City, UT, United States.ORCID http://orcid.org/0000-0002-7159-9239
Chelsey SchlechterHuntsman Cancer Institute, Salt Lake City, UT, United States.ORCID http://orcid.org/0000-0002-8355-6316
Ravi N SharafWeill Cornell Medicine, New York City, NY, United States.ORCID http://orcid.org/0000-0002-6905-9823
Kensaku KawamotoDepartment of Biomedical Informatics, University of Utah, Salt Lake City, UT, United States.ORCID http://orcid.org/0000-0003-4282-9338
Guilherme Del FiolDepartment of Biomedical Informatics, University of Utah, Salt Lake City, UT, United States.ORCID http://orcid.org/0000-0001-9954-6799
Kimberly A KaphingstDepartment of Communication, University of Utah, 255 S Central Campus Dr, Salt Lake City, UT, 84112, United States, 1 801-581-6889.ORCID http://orcid.org/0000-0003-2668-9080

Funding

GARDE: Scalable Clinical Decision Support for Individualized Cancer Risk ManagementU24CA274582 · NCI · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI GUILHERME DEL FIOL, Kensaku Kawamoto · 2023 to 2026
$3.3M
NCI NIH HHS U24 CA274582
6 · The paper itself

Abstract

Background: Digital health tools, such as health chatbots, may improve access to scalable health support, but adoption remains inconsistent. Existing models do not fully integrate technology acceptance factors with health motivation factors relevant to digital health use. Objective: This study proposed and tested the health technology acceptance model and examined whether normative message framing and chatbot type were associated with health motivation, technology acceptance, and intention to use a health chatbot. Methods: In October 2025, we conducted a 4 × 2 between-participants online experiment with 1000 US adults recruited from a nationally representative YouGov panel. Participants were randomized to 1 of 8 conditions varying norm message type (self-oriented, peer-oriented, expert-oriented, or family-oriented) and chatbot type (AI-powered or rule-based) in a cancer prevention and genetic risk information scenario. Outcomes included descriptive norms, injunctive norms, perceived susceptibility, perceived severity, perceived benefits, self-efficacy, perceived ease of use, trust, privacy concerns, and usage intention. Data were analyzed using a multivariate ANOVA with Bonferroni-adjusted post hoc tests and multiple linear regression. Results: Peer-oriented and family-oriented messages produced higher usage intention than expert-oriented messages, and peer-oriented messages also increased descriptive norms, injunctive norms, self-efficacy, and trust. AI-powered chatbots were associated with higher usage intention ( Conclusions: The health technology acceptance model was a useful framework for explaining the intention to use a health chatbot by combining technology acceptance and health motivation constructs. Both social design features and chatbot design features shaped adoption-related beliefs, with peer-oriented and family-oriented framing and AI-powered chatbots showing particular promise. Trust and privacy concerns remained central determinants of intended use.

Indexed as

IntentionAdultDigital HealthFemaleHumansMaleMiddle AgedMotivationYoung AdultAIchatbotdigital healthsocial normtechnology acceptance

Identifiers

PMID42743590
PMCPMC13577661

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.