Evidence map›Paper›PMID 42742875›Full record

ReviewCurrent nutrition reports2026

Hemodynamic-Guided Nutrition Support in Pediatric Congenital Heart Disease.

Akash Pandey, Jithinraj Edakkanambeth Varayil, Craig E Fleishman, Senthilkumar Sankararaman

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current nutrition reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Akash PandeyDivision of Pediatric Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, Orlando Health Arnold Palmer Hospital for Children, Orlando, FL, USA. akash.pandey@orlandohealth.com.
Jithinraj Edakkanambeth VarayilDepartment of Family Medicine, Mayo Clinic, Rochester, MN, USA.
Craig E FleishmanDivision of Pediatric Cardiology, Department of Pediatrics, Orlando Health Arnold Palmer Hospital for Children, Orlando, FL, USA.
Senthilkumar SankararamanDivision of Pediatric Gastroenterology, Hepatology, and Nutrition, Cleveland Clinic Children's Hospital, Cleveland, OH, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewChildren with congenital heart disease (CHD) are at high risk of malnutrition, feeding difficulties and altered body composition beyond infancy. Nutritional decisions are often based on cardiac anatomy. Although anatomy alone does not capture differences in metabolic demand, mesenteric perfusion and feeding intolerance. This review presents physiology-based framework to guide nutritional support in pediatric CHD care pathway. RECENT

findingsRecent evidence favors early enteral feeding when hemodynamically appropriate, prioritizing human milk in high-risk infants, standardizing perioperative feeding protocols, assessment beyond weight alone and early attention to oral feeding skills. Long term concern includes micronutrition deficiency, protein losing enteropathy, sarcopenia, obesity and feeding difficulties. Some evidence remains unclear in several areas including exact calorie and protein goal, hemodynamic feeding threshold, weight loss medications in pediatric CHD. Five hemodynamic categories (systemic hypoperfusion, global hypoxia, pulmonary over circulation, mixing lesions, and single-ventricle physiology) may providea practical way to guide nutrition decisions than anatomic diagnosis alone. Matching feeding strategy to mesenteric perfusion, metabolic demand, and complication risk may improve consistency of care but pediatric-specific prospective studies stratified by hemodynamic physiology with patient-centered endpoints are needed.

Indexed as

Heart Defects, CongenitalHemodynamicsMalnutritionNutritional SupportChildChild, PreschoolEnteral NutritionHumansInfantInfant, NewbornNutritional StatusCardiac cachexiaCongenital heart diseaseEnteral nutritionFeeding aversionFontanHemodynamic stratificationMalnutritionNecrotizing enterocolitisPediatric nutritionPerioperative care

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.