Evidence map›Paper›PMID 42742750›Full record

ArticlePediatric surgery international2026

Comparison of long-term outcomes and nutritional status between primary and non-primary fascial closure in omphalocele.

Poohpathra Burapharat, Nimmita Srisan, Kanokrat Thaiwatcharamas, Patchareeporn Tanming, Dolrudee Aroonsaeng, Paisarn Vejchapipat, Sinobol Chusilp

Abstract readComparative StudyMulticenter Study
PubMed Publisher
In one paragraph

Article in Pediatric surgery international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Poohpathra BurapharatDivision of Pediatric Surgery, Department of Surgery, Faculty of Medicine, Khon Kaen University, 123 Mittraphap Road, Khon Kaen, 40002, Thailand.
Nimmita SrisanDivision of Pediatric Surgery, Department of Surgery, Faculty of Medicine, Chulalongkorn University, King Chulalongkorn Memorial Hospital, Bangkok, 10330, Thailand.
Kanokrat ThaiwatcharamasDivision of Pediatric Surgery, Department of Surgery, Faculty of Medicine, Khon Kaen University, 123 Mittraphap Road, Khon Kaen, 40002, Thailand.
Patchareeporn TanmingDivision of Pediatric Surgery, Department of Surgery, Faculty of Medicine, Khon Kaen University, 123 Mittraphap Road, Khon Kaen, 40002, Thailand.
Dolrudee AroonsaengDivision of Pediatric Surgery, Department of Surgery, Faculty of Medicine, Khon Kaen University, 123 Mittraphap Road, Khon Kaen, 40002, Thailand.
Paisarn VejchapipatDivision of Pediatric Surgery, Department of Surgery, Faculty of Medicine, Chulalongkorn University, King Chulalongkorn Memorial Hospital, Bangkok, 10330, Thailand.
Sinobol ChusilpDivision of Pediatric Surgery, Department of Surgery, Faculty of Medicine, Khon Kaen University, 123 Mittraphap Road, Khon Kaen, 40002, Thailand. sinoch@kku.ac.th.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeOperative strategies for omphalocele vary, and long-term outcomes remain limited. We aimed to compare postoperative and long-term outcomes of omphalocele repair with primary versus non-primary fascial closure.

methodsA retrospective study of omphalocele at 2 institutions between 2006 and 2021 was conducted. After excluding patients with genetic disorders and severe associated anomalies, 41 patients (15 primary fascial and 26 non-primary fascial closures) were reviewed.

resultsAlthough there were no significant differences in defect size or liver herniation, non-primary fascial closure was significantly associated with a concomitant non-cyanotic cardiac anomaly. Time to first enteral feeding and length of hospital stay were significantly longer in non-primary fascial closure. For long-term outcomes, non-primary fascial closure was associated with significantly higher rates of failure to thrive during infancy (76% vs. 40%) and toddlerhood (62.5% vs. 23.1%). However, there were no significant differences in ventral hernia, respiratory, or neurodevelopmental problems.

conclusionNon-primary fascial closure is associated with higher rates of failure to thrive, underscoring need for long-term follow-up of nutritional status; however, the higher incidence of cardiac anomalies in this group may reflect a bias toward selecting this closure technique. When feasible and not complicated, primary fascial closure might be preferred option for omphalocele.

Indexed as

Abdominal Wound Closure TechniquesFasciotomyHernia, UmbilicalNutritional StatusOmphaloceleFemaleFollow-Up StudiesHumansInfantInfant, NewbornMaleRetrospective StudiesTreatment OutcomeFailure to thriveLong-term outcomeOmphalocelePrimary fascial closure

Identifiers

PMID42742750

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