Evidence map›Paper›PMID 42742717›Full record

ArticleTAG. Theoretical and applied genetics. Theoretische und angewandte Genetik2026

Identification of septoria nodorum blotch susceptibility genes in hard winter wheat.

Anju Maan Ara, Danielle J Holmes, Timothy L Friesen, Brett F Carver, Guihua Bai, Paul St Amand, Amy Bernado, Rajat Sharma, Meriem Aoun

Abstract read
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Article in TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Anju Maan AraDepartment of Entomology and Plant Pathology, Oklahoma State University, Stillwater, OK, USA.
Danielle J HolmesCereal Crops Improvement Research Unit, USDA-ARS, Fargo, ND, USA.
Timothy L FriesenCereal Crops Improvement Research Unit, USDA-ARS, Fargo, ND, USA.
Brett F CarverDepartment of Plant and Soil Sciences, Oklahoma State University, Stillwater, OK, USA.
Guihua BaiDepartment of Agronomy, Kansas State University, Manhattan, KS, USA.
Paul St AmandHard Winter Wheat Genetics Research Unit, USDA-ARS, Manhattan, KS, USA.
Amy BernadoHard Winter Wheat Genetics Research Unit, USDA-ARS, Manhattan, KS, USA.
Rajat SharmaDepartment of Entomology and Plant Pathology, Oklahoma State University, Stillwater, OK, USA.
Meriem AounDepartment of Entomology and Plant Pathology, Oklahoma State University, Stillwater, OK, USA. meriem.aoun@okstate.edu.

Funding

National Institute of Food and Agriculture 2024-67013-42587
6 · The paper itself

Abstract

key messageCharacterized and unknown septoria nodorum blotch sensitivity/resistance genes were identified in contemporary US hard winter wheat. The necrotrophic fungus Parastagonospora nodorum is the causal agent of septoria nodorum blotch (SNB) of wheat. To determine the prevalence of SNB sensitivity genes in a contemporary US hard winter wheat (HWW), we evaluated a panel of 619 breeding lines and cultivars against five P. nodorum isolates and five necrotrophic effectors (NEs), SnToxA, SnTox1, SnTox3, SnTox267, and SnTox5, and genotyped the panel using genotyping-by-sequencing (GBS) markers and diagnostic kompetetive allele-specific PCR (KASP) markers for the sensitivity genes Tsn1-B1, Snn1-B1, and Snn3-B1/B2. GBS analysis identified 34,357 GBS-single-nucleotide polymorphism (SNP) markers. Evaluations against P. nodorum isolates showed that 40-67% of the genotypes were susceptible in the panel. Toxin infiltration assays showed that 54%, 2%, 37%, 13%, and 15% of the genotypes were sensitive to SnToxA, SnTox1, SnTox3, SnTox267, and SnTox5, respectively. Diagnostic KASP markers for Tsn1-B1, Snn1-B1, and Snn3-B1/B2 showed prediction accuracies of 98%, 75%, and 92% for the corresponding effectors SnToxA, SnTox1, and SnTox3, respectively. Genome-wide association studies (GWAS) not only confirmed the presence of the previously characterized sensitivity genes Tsn1-B1, Snn1-B1, Snn2, Snn3-B1/B2, and Snn5-B1, but also identified new loci to be associated with responses to P. nodorum isolates and NEs. Of these, Qsnb.osu-2AS on chromosome 2AS was associated with responses to all five isolates. KASP markers linked to Snn5-B1, Snn2, and Qsnb.osu-2AS were developed for potential use in marker-assisted selection. These findings should guide breeding for SNB resistance in hard winter wheat.

Indexed as

AscomycotaDisease ResistanceGenes, PlantPlant DiseasesTriticumAllelesChromosome MappingGenetic MarkersGenotypePhenotypePolymorphism, Single NucleotideGenetic Markers

Identifiers

PMID42742717
PMCPMC13578052

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.