Evidence map›Paper›PMID 42742407›Full record

ArticleRheumatology (Oxford, England)2026

Digital home monitoring in patients with juvenile idiopathic arthritis to increase intervals of hospital visits.

Anne Jasmijn Sellies, Joeri W van Straalen, Gerrie C J de Joode-Smink, Martijn J H Doeleman, Marc H A Jansen, Erika Van Nieuwenhove, Annet van Royen-Kerkhof, Bas J Vastert, Nico M Wulffraat, Sytze de Roock and 1 more

Registry-linked trialAbstract readEquivalence Trial
In one paragraph

Article in Rheumatology (Oxford, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05603286 (Testing an Increased Visit Interval scHeme UsIng Web-based Self-evaluation in Patients With Juvenile Idiopathic Arthritis), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05603286 nacompletednot on this map

Testing an Increased Visit Interval scHeme UsIng Web-based Self-evaluation in Patients With Juvenile Idiopathic Arthritis

TypeinterventionalSponsorJoeri van StraalenRan2022 to 2023Enrolled85ConditionsJIA, Self-EvaluationArmsHome-monitoring
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Anne Jasmijn SelliesDepartment of Paediatric Immunology and Rheumatology, Wilhelmina Children's Hospital, University Medical Centre Utrecht, Utrecht, The Netherlands.ORCID 0000-0003-4776-7914
Joeri W van StraalenDepartment of Paediatric Immunology and Rheumatology, Wilhelmina Children's Hospital, University Medical Centre Utrecht, Utrecht, The Netherlands.
Gerrie C J de Joode-SminkDepartment of Paediatric Immunology and Rheumatology, Wilhelmina Children's Hospital, University Medical Centre Utrecht, Utrecht, The Netherlands.
Martijn J H DoelemanDepartment of Paediatric Immunology and Rheumatology, Wilhelmina Children's Hospital, University Medical Centre Utrecht, Utrecht, The Netherlands.ORCID 0000-0003-4786-4108
Marc H A JansenDepartment of Paediatric Immunology and Rheumatology, Wilhelmina Children's Hospital, University Medical Centre Utrecht, Utrecht, The Netherlands.
Erika Van NieuwenhoveDepartment of Paediatric Immunology and Rheumatology, Wilhelmina Children's Hospital, University Medical Centre Utrecht, Utrecht, The Netherlands.
Annet van Royen-KerkhofDepartment of Paediatric Immunology and Rheumatology, Wilhelmina Children's Hospital, University Medical Centre Utrecht, Utrecht, The Netherlands.
Bas J VastertDepartment of Paediatric Immunology and Rheumatology, Wilhelmina Children's Hospital, University Medical Centre Utrecht, Utrecht, The Netherlands.
Nico M WulffraatDepartment of Paediatric Immunology and Rheumatology, Wilhelmina Children's Hospital, University Medical Centre Utrecht, Utrecht, The Netherlands.
Sytze de RoockDepartment of Paediatric Immunology and Rheumatology, Wilhelmina Children's Hospital, University Medical Centre Utrecht, Utrecht, The Netherlands.
Joost F SwartDepartment of Paediatric Immunology and Rheumatology, Wilhelmina Children's Hospital, University Medical Centre Utrecht, Utrecht, The Netherlands.ORCID 0000-0002-2759-2822

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesJuvenile Idiopathic Arthritis (JIA) patients attend routine hospital check-ups, even when disease activity is low. These visits are time-consuming and costly. Replacing visits with home monitoring may reduce costs but should not affect safety and (perceived) quality of care. This non-inferiority study tested whether patients with inactive JIA could safely prolong visit-intervals by home monitoring disease activity using EuroQol EQ-5D-Y-5L and Juvenile Arthritis Multidimensional Assessment Report questionnaires.

methodsOne regular 3-monthly visit was replaced by home monitoring. Healthcare professionals evaluated responses to determine whether patients could safely prolong their visit-interval or needed a doctor's consultation. Flare percentages over the total study period and 6 months after baseline were compared with a historical flare percentage and with matched JIA patients using relative risks (RR) and a non-inferiority margin of 15%. Secondary outcomes were number of reminders, number of patients not completing home monitoring and patient satisfaction.

resultsEighty-four patients aged between 6 and 20 years participated in the study. Eighteen patients had a visit before or after evaluation of the questionnaires. Sixty-three had a prolonged interval, of whom seven experienced a flare. The study-wide flare percentage was 18.5%, the historical flare percentage was 18.4% (including non-inferiority margin). The RR for study-wide flares was 0.50 (95%CI: 0.29-0.86), showing non-inferiority. The study was underpowered for comparing flares after prolonged visit-intervals (RR: 0.77, 0.30-1.93). Overall, 92% showed interest in home monitoring more often.

conclusionNo clear evidence was found that increased visit-intervals with home monitoring poses a risk for missing disease flares. Reminders were necessary and patient satisfaction was high.

trial registrationClinicaltrials.gov.uk; NCT05603286.

Indexed as

Arthritis, JuvenileAdolescentChildDigital HealthFemaleHumansMalePatient SatisfactionRemote Patient MonitoringSurveys and QuestionnairesYoung Adultdelivery of health caredisease activityinterventional studiesjuvenile idiopathic arthritisorganization of health careoutcome measurespaediatric/juvenile/child/adolescentpatient-reported outcomesquality of health caretelemedicine

Identifiers

PMID42742407
PMCPMC13649185

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.