Evidence map›Paper›PMID 42742248›Full record

ReviewJournal of applied microbiology2026

Host-microbiome interactions and enteric pathogen infections-from early-life to long-term impacts on gut-brain communication.

Mélanie G Gareau, Jungjae Park, Kim E Barrett

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of applied microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Mélanie G GareauDepartment of Anatomy, Physiology, and Cell Biology, School of Veterinary Medicine, University of California, Davis, Davis, CA 95616, United States.
Jungjae ParkDepartment of Anatomy, Physiology, and Cell Biology, School of Veterinary Medicine, University of California, Davis, Davis, CA 95616, United States.
Kim E BarrettDepartment of Physiology and Membrane Biology, School of Medicine, University of California, Davis, Sacramento, CA 95817, United States.ORCID 0000-0002-6704-998X

Funding

Impact of developmental exposure to PFAS on the microbiota-gut-brain axisR21ES034806 · NIEHS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI GAREAU, MELANIE G, REARDON, COLIN · 2023 to 2023
$424k
NIEHS NIH HHS R21 ES034806NIH HHS ES034806
6 · The paper itself

Abstract

Interactions of the host with the microbes that constitute the intestinal microbiota are important for maintaining health and well-being within the gastrointestinal tract and beyond. Disruptions to these interactions, such as those that follow enteric pathogen infection or administration of antibiotics, can lead to persistent pathophysiology, particularly if disruptions occur during early development in neonatal life. Here, we highlight the impacts of altered host-microbe interactions following insults across the life span and discuss emerging mechanisms of action promoting these disruptions (see Graphical Abstract). We also identify potential therapeutics to restore these important pathways and their mechanisms of action.

Indexed as

BrainGastrointestinal MicrobiomeGastrointestinal TractHost Microbial InteractionsHost-Pathogen InteractionsAnimalsAnti-Bacterial AgentsHumansAnti-Bacterial Agentsgut-brain axishost-microbe interationsintestinal pathogenMicrobiome

Identifiers

PMID42742248
PMCPMC13662926

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.