ArticleNature2026
Learning millisecond protein dynamics from what is missing in NMR spectra.
Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed.
- AI-based methods for simulating, sampling, and predicting protein ensembles.Current opinion in structural biology · 2026Review
- Black-box data: a new paradigm for biomedicine in the AI era.Chemical science · 2026Review
- Article
- Generation of protein dynamics by machine learning.Current opinion in structural biology · 2025Review
- Structure-Based Experimental Datasets for Benchmarking Protein Simulation Force Fields [Article v1.0].Living journal of computational molecular science · 2025Article
- Excessive Existence of Positively Charged Amino Acids Caused Off-Target Recognition in the Seed Region ofInternational journal of molecular sciences · 2025Article
Corrections and comments
- Update of
Authors and funding
7 authors.
Funding
Abstract
The biological functions of many proteins rely on interconversions between multiple conformations occurring at microsecond to millisecond (µs-ms) timescales. A lack of standardized, large-scale experimental data has hindered obtaining a more predictive understanding of these motions. Here, after curating over 100 nuclear magnetic resonance (NMR) relaxation datasets, we found that an observable for µs-ms dynamics may have been overlooked. Millisecond dynamics can cause NMR signals to broaden beyond detection, leaving some residues not assigned in the chemical shift datasets of around 10,000 proteins deposited in the Biological Magnetic Resonance Data Bank (BMRB)
Identifiers
42742167What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.