Evidence map›Paper›PMID 42742111›Full record

ArticleEmerging microbes & infections2026

ESAT-6-derived lipopeptide-based mucosal vaccine elicits distinct humoral immune responses concomitant with a reduction in

Shanika Werellagama, Nancy Gupta, Jie Li, Rakesh Kumar, Babita Agrawal

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Emerging microbes & infections, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shanika WerellagamaDepartment of Surgery, University of Alberta, Edmonton, Canada.
Nancy GuptaDepartment of Laboratory Medicine and Pathology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Canada.
Jie LiDepartment of Surgery, University of Alberta, Edmonton, Canada.
Rakesh KumarDepartment of Laboratory Medicine and Pathology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Canada.
Babita AgrawalDepartment of Surgery, University of Alberta, Edmonton, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Respiratory mycobacterial infections remain a major global health threat, yet current vaccine strategies, which focus primarily on cell-mediated immunity, have met with limited success. We previously demonstrated that a vaccine composed of five lipopeptides (LPs) encoding immunodominant ESAT-6 epitopes elicits protective cellular immune responses against

Indexed as

Antigens, BacterialBacterial ProteinsBacterial VaccinesImmunity, HumoralLipopeptidesTuberculosisAnimalsAntibodies, BacterialDisease Models, AnimalFemaleImmunity, CellularImmunity, MucosalImmunoglobulin AImmunoglobulin GLungMiceAntibodies, BacterialAntigens, BacterialBacterial ProteinsBacterial VaccinesESAT-6 protein, Mycobacterium tuberculosisImmunoglobulin AImmunoglobulin GLipopeptidesProtein Subunit VaccinesantibodyESAT-6immunotherapylipopeptideMycobacterial infectionsprophylactic

Identifiers

PMID42742111
PMCPMC13618096

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.