ArticleChemistry & biodiversity2026
Two New Polyketides From Streptomyces sp. SA61: Isolation, Structure Elucidation, and Insecticidal Activity Against Bemisia tabaci.
Article in Chemistry & biodiversity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
To discover novel green bio-based insecticidal lead compounds, six polyketides, including two new compounds, strekingmycin I (5) and strekingmycin J (6), together with four known analogues, were isolated and identified from the fermentation products of earthworm gut-derived Streptomyces sp. SA61. Their structures were established by comprehensive spectroscopic analysis, including NMR, HR-ESI-MS, and single-crystal x-ray diffraction. Notably, the crystallographic data of strekingmycin G (3) were obtained for the first time, which unambiguously confirmed its absolute configuration. In insecticidal activity assays against the third-instar nymphs of Bemisia tabaci, all six compounds exhibited varying degrees of toxicity. Among them, strekingmycin A (1) displayed the most potent activity, with an LC
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