Evidence map›Paper›PMID 42741690›Full record

ArticleiScience2026

Biocompatibility and antibacterial properties of ordered PLA fiber membranes fabricated via electrospinning technology.

Donghe Xue, Zhen Zhang, Zeyu Zhang, Xiaohu Zheng, Jialong Xu, Yao Chen, Zuo Liu, Junwen Gu, Hao Lu, Kun Li and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Donghe XueOrthopedic Center, Xiuzhou District People's Hospital, Jiaxing, Zhejiang 314015, China.
Zhen ZhangDepartment of Biotechnology and Bio Medicine, Yangtze Delta Region Institute of Tsinghua University, Jiangxing 314006, Zhejiang, China.
Zeyu ZhangOrthopedic Center, Xiuzhou District People's Hospital, Jiaxing, Zhejiang 314015, China.
Xiaohu ZhengOrthopedic Center, Xiuzhou District People's Hospital, Jiaxing, Zhejiang 314015, China.
Jialong XuOrthopedic Center, Xiuzhou District People's Hospital, Jiaxing, Zhejiang 314015, China.
Yao ChenOrthopedic Center, Xiuzhou District People's Hospital, Jiaxing, Zhejiang 314015, China.
Zuo LiuOrthopedic Center, Xiuzhou District People's Hospital, Jiaxing, Zhejiang 314015, China.
Junwen GuOrthopedic Center, Xiuzhou District People's Hospital, Jiaxing, Zhejiang 314015, China.
Hao LuDepartment of Biotechnology and Bio Medicine, Yangtze Delta Region Institute of Tsinghua University, Jiangxing 314006, Zhejiang, China.
Kun LiDepartment of Biotechnology and Bio Medicine, Yangtze Delta Region Institute of Tsinghua University, Jiangxing 314006, Zhejiang, China.
Longwei LuOrthopedic Center, Xiuzhou District People's Hospital, Jiaxing, Zhejiang 314015, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peripheral nerve injury remains a major clinical challenge owing to its limited self-regeneration capacity and high risk of postoperative infection. In this study, highly ordered poly(lactic acid) (PLA) nanofiber membranes were fabricated via electrospinning and loaded with 2.0% moxifloxacin to achieve the dual functions of axonal guidance and localized antibacterial activity. Morphological characterization revealed uniform fiber diameters, parallel orientation, and interconnected porosity, with favorable mechanical properties and an appropriate hydrophilic-hydrophobic balance.

Indexed as

antibacterialbiocompatibilityelectrospinning technologynanofiber membranesSchwann cells

Identifiers

PMID42741690
PMCPMC13573699

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.