ArticleFrontiers in surgery2026
Sodium fluorescein in pediatric brain tumor surgery: a retrospective volumetric analysis of resection extent and consistency.
Article in Frontiers in surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: Maximizing the extent of resection (EOR) while preserving neurological function remains a key challenge in pediatric brain tumor surgery. Sodium fluorescein (SF) has been proposed as an adjunct to improve intraoperative visualization; however, evidence in pediatric populations is limited. This study evaluated the association between SF use and EOR, including the consistency of surgical outcomes. Methods: A retrospective single-center cohort of 58 pediatric patients (19 SF, 39 control) with intended gross total resection (GTR) was analyzed. EOR was assessed using postoperative volumetric MRI. Given the retrospective design and histological heterogeneity, analyses were considered exploratory. Results: The SF group showed greater mean EOR (99.67% ± 1.46 vs. 96.32% ± 11.53; Conclusion: SF-guided surgery was associated with a modestly greater extent of resection and significantly higher GTR rate in selected pediatric brain tumors, predominantly pilocytic astrocytomas, with reduced EOR dispersion as a secondary finding. Given the retrospective design, limited sample size, and potential confounding-including the
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.