ArticleFrontiers in nutrition2026
Effect of different chitosan molecular weights on microplastic excretion.
Article in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: Microplastic (MP) ingestion poses a considerable health risk to organisms, including humans, and the environment. The previously established average molecular weight of chitosan that promotes MP excretion is approximately 800,000; however, the effects of chitosan with different molecular weights on MP excretion and the intestinal environment remain unclear. This study aimed to clarify the effects of different chitosan molecular weights on MP excretion and gut microbiota. Methods: Sprague-Dawley rats were fed a diet containing MPs with an average particle size of 50 μm. Results: Compared with the control group, fecal weight increased in all chitosan groups across different molecular weights (low: 83,000; medium: 673,000; high: 1,877,000). Furthermore, the medium and high molecular weight chitosan groups exhibited a significantly higher MP excretion rate and lower MP retention rate in the gastrointestinal tract. The
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