ArticleCureus2026
Late-Onset Neonatal Cyanosis Secondary to Methemoglobinemia in a Preterm, Small-for-Gestational-Age Infant: A Case Report.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
2 authors.
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Abstract
Methemoglobinemia is a rare cause of neonatal cyanosis stemming from hemoglobin iron oxidation, creating susceptibility due to immature enzymatic systems in newborns. This case study details a 32-week preterm infant presenting with unexplained desaturations (oxygen saturation (SpO2): 82-90%) on day of life 13, which were resolved with intravenous methylene blue and oral vitamin C after co-oximetry confirmed 18% methemoglobin. Prompt diagnosis and low-dose targeted therapy are essential for managing this condition in fragile, preterm neonates with persistent central cyanosis.
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