Evidence map›Paper›PMID 42741110›Full record

ArticleFrontiers in public health2026

Innovations in reagent manufacturing to support the global diagnostics supply chain.

Anna R Bird, Jacqueline C Linnes, Laud Anthony Basing, Elizabeth A H Hall

Abstract read
In one paragraph

Article in Frontiers in public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Anna R BirdImperial Global Singapore, Imperial College London, London, United Kingdom.
Jacqueline C LinnesWeldon School of Biomedical Engineering, Purdue University, West Lafayette, IN, United States.
Laud Anthony BasingDepartment of Medical Diagnostics, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Elizabeth A H HallDepartment of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diagnostics are not only tools for clinical decision making, but also drivers of the healthcare supply chain. They quantify and monitor the prevalence of disease across global populations. At high levels, this population health data is used to inform the purchasing and distribution of health care goods. There is overwhelming evidence that access to diagnostics is limited in low-and middle-income countries. This is true for both in-vitro molecular diagnostics and diagnostic imaging, but the scope of this work is limited to the former. While the factors contributing to limited access are numerous, interconnected, and complex, we propose a method to alleviate some restraints within the supply chain: distributed and local manufacturing of key biological reagents, or active diagnostics ingredients (ADIs). In addition to shifting the geographical boundaries of manufacturing and moving goods closer to areas of deployment, this could reduce global power imbalances by redistributing ownership of diagnostics goods, reagents, and intellectual property.

Indexed as

Global HealthMolecular Diagnostic TechniquesDeveloping CountriesHumansIndicators and ReagentsTechnology TransferIndicators and Reagentsdistributed manufacturingglobal health equitylow-cost diagnosticsmolecular diagnosticstechnology transfer

Identifiers

PMID42741110
PMCPMC13572216

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.