ArticleAmerican heart journal plus : cardiology research and practice2026
Arrhythmic risk in ventricular cardiac tumors: A comparative imaging and clinical analysis.
Article in American heart journal plus : cardiology research and practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Ventricular arrhythmias and sudden cardiac death (SCD) are serious complications of cardiac tumors, but predictors of arrhythmic risk in patients with ventricular masses remain poorly defined. Objective: To identify clinical, anatomical, and imaging features associated with ventricular arrhythmia/SCD (VA/SCD) presentation in patients with ventricular cardiac masses. Methods: We performed a retrospective comparative cohort study using a prospectively maintained registry at Aswan Heart Centre including patients with ventricular cardiac masses (2012-2024). Patients with sustained ventricular tachyarrhythmia, survived sudden cardiac arrest, or arrhythmic death were classified as the VA/SCD group and compared with patients without significant ventricular arrhythmia. Continuous variables were compared using Mann-Whitney Results: Among 34 patients, 11 (32.4%) had VA/SCD presentation during a median follow-up of 3 years. The VA/SCD group was older (14 vs. 1 year, Conclusions: VA/SCD presentation in ventricular cardiac masses is associated with a phenotype of larger size, solitary morphology, and arrhythmogenic histology rather than impaired ventricular function. But these patterns were confounded by tumor type, especially pediatric multifocal rhabdomyomas.
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