ArticleRespiratory research & clinical practice2026
Differences in survival between two cohorts of COPD patients living in Mexico City: a 20-year cohort comparison.
Article in Respiratory research & clinical practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: To compare the survival rates for two cohorts of COPD patients living in Mexico City and studied 20 years apart at the same referral center, with demographic characteristics, lung function, hypoxemia, type of exposure associated with COPD, and socioeconomic status being analyzed. Methods: Two cohorts of COPD patients were studied and followed at a single referral center for respiratory diseases in Mexico City, at an altitude of 2,240 m above sea level. The first cohort was studied between 1996 and 2003, and the second was studied between 2016 and 2023. Participants were followed for seven years, and a multivariate Cox model was used in order to analyze survival. Results: The first cohort included 434 patients, and the second comprised 416 patients, with a total of 850 patients being analyzed. Of those, 68% had COPD from tobacco smoking and 32% had COPD from biomass smoke exposure. In the multivariate Cox model adjusted for age, sex, smoking status, exposure to biomass smoke, BMI < 21 kg/m Conclusions: Survival of COPD patients has improved over the past 20 years after accounting for several mortality predictors.
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