ArticleiScience2026
Topology-preserved transformer-based CBCT-CT registration via normalized gradient field guidance for nasopharyngeal carcinoma.
Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Accurate deformable registration between planning CT (computed tomography) and cone-beam CT (CBCT) is essential for adaptive radiotherapy in nasopharyngeal carcinoma, but cross-modality intensity differences, low soft-tissue contrast, and CBCT artifacts complicate alignment. We propose NJTransMorph, an unsupervised transformer-based registration framework that integrates normalized gradient field loss and Jacobian determinant regularization to improve multimodal structural alignment and deformation plausibility. NJTransMorph was evaluated against VoxelMorph, UTSRMorph, and TransMorph on an internal cohort (
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