Evidence map›Paper›PMID 42740805›Full record

ArticleiScience2026

Rethinking chemical clusters: Greenfield and brownfield transition to net-zero by 2050.

Julia L Tiggeloven, André P C Faaij, Gert Jan Kramer, Matteo Gazzani

Abstract read
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Julia L TiggelovenUtrecht University, Copernicus Institute of Sustainable Development, Princetonlaan 8a, 3584 CB Utrecht, the Netherlands.
André P C FaaijUtrecht University, Copernicus Institute of Sustainable Development, Princetonlaan 8a, 3584 CB Utrecht, the Netherlands.
Gert Jan KramerUtrecht University, Copernicus Institute of Sustainable Development, Princetonlaan 8a, 3584 CB Utrecht, the Netherlands.
Matteo GazzaniUtrecht University, Copernicus Institute of Sustainable Development, Princetonlaan 8a, 3584 CB Utrecht, the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We develop a cluster-level optimization framework to design brownfield transition pathways toward net-zero chemical clusters by 2050, applied to existing ammonia-olefin clusters in the Netherlands. The model represents sequential investment decisions for 2030, 2040, and 2050, includes scope 1-3 emissions, and enables a systematic comparison of greenfield and brownfield configurations. Thirteen olefin and eight ammonia production routes are considered. The results show that, despite reduced flexibility due to legacy assets, net-zero brownfield configurations remain feasible. Plastic gasification combined with methanol-to-olefins emerges as a low-regret option for olefins, while electric steam methane reforming and electrolyzers are robust choices for ammonia. The results support early investment rather than strategic delay. Excluding scope 3 emissions leads to lock-in of fossil-based options that appear cost-effective short-term but raise long-term system costs. Sensitivity analyses highlight uncertainties related to infrastructure and technology availability, bio-feedstock prices, and plastic waste emission accounting.

Indexed as

brownfield transformationchemical clustersMILPmixed integer linear programmingmulti-period optimizationnet-zero emissionsscope 1–3 emissionstransition pathways

Identifiers

PMID42740805
PMCPMC13571977

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.