Evidence map›Paper›PMID 42740797›Full record

ArticleAdvances in ophthalmology practice and research

Fifteen-year follow-up of implantable collamer lens surgery in high myopia: Complications, cataract surgery outcomes, and ultrastructural analysis.

Yinjie Jiang, Guanghan Xu, I-Chun Lin, Mingrui Cheng, Boliang Li, Yadi Lei, Mingwei Li, Zhiwei Mao, Rui Ning, Xun Chen and 1 more

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Article in Advances in ophthalmology practice and research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Yinjie JiangFudan University Eye Ear Nose and Throat Hospital, Shanghai, China.
Guanghan XuFudan University Eye Ear Nose and Throat Hospital, Shanghai, China.
I-Chun LinFudan University Eye Ear Nose and Throat Hospital, Shanghai, China.
Mingrui ChengFudan University Eye Ear Nose and Throat Hospital, Shanghai, China.
Boliang LiFudan University Eye Ear Nose and Throat Hospital, Shanghai, China.
Yadi LeiFudan University Eye Ear Nose and Throat Hospital, Shanghai, China.
Mingwei LiFudan University Eye Ear Nose and Throat Hospital, Shanghai, China.
Zhiwei MaoFudan University Eye Ear Nose and Throat Hospital, Shanghai, China.
Rui NingFudan University Eye Ear Nose and Throat Hospital, Shanghai, China.
Xun ChenFudan University Eye Ear Nose and Throat Hospital, Shanghai, China.
Xiaoying WangFudan University Eye Ear Nose and Throat Hospital, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purposes: This study reports 15-year outcomes of implantable collamer lens (ICL) surgery in patients with high myopia, analyzing complications, efficacy of cataract surgical, and ultrastructural mechanisms of anterior subcapsular cataract (ASC). Methods: This retrospective study included 1208 eyes (ICL V4) and 6258 eyes (ICL V4c) from Eye & ENT Hospital of Fudan University, Shanghai, China. Follow-ups occurred preoperatively, at 1/3/6 months, annually post-ICL, and 1 month post-cataract surgery. Lens opacity, ASC rates, and complications were evaluated. Anterior capsule ultrastructure was assessed using scanning/transmission electron microscopy (SEM/TEM). Results: The ICL V4 group (follow-up: 23.12 ± 32.06 months) exhibited higher complication rates than V4c (8.95 ± 17.40 months): lens opacity (6.46% vs. 0.16%), ASC (2.32% vs. 0.10%), and bilensectomy (3.89% vs. 0.16%). Bilensectomy improved corrected distance visual acuity from 0.56 ± 0.39 to 0.34 ± 0.51 logMAR ( Conclusions: Super high myopia, shallow anterior chamber depth, and older age are key risk factors for post-ICL cataract. While bilensectomy restores vision, high myopia-related complications persist. ASC pathogenesis involves mechanical damage and metabolic dysfunction, evidenced by ultrastructural changes. These findings underscore the need for long-term monitoring in ICL patients with high myopia.

Indexed as

Anterior subcapsular cataractComplicationsHigh myopiaICL V4ICL V4cPhakic intraocular lens

Identifiers

PMID42740797
PMCPMC13572004

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.