Evidence map›Paper›PMID 42740756›Full record

ArticleClinical and public health guidelines2025

Consolidation, Systematic Appraisal and Comparison of Guideline Recommendations Regarding Management of Chronic Pain: Protocol for a Digital Chronic Pain Recommendation Map.

Andrea J Darzi, Kian Torabiardakani, Gonzalo Bravo-Soto, Daniela Montalva-Romero, Rachel J Couban, Lynn Cooper, Stacey Ritz, Jaris Swidrovich, Ivan D Florez, Vivian Welch and 4 more

Abstract read
In one paragraph

Article in Clinical and public health guidelines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Andrea J DarziDepartment of Health Research Methods, Evidence, and Impact McMaster University Hamilton Ontario Canada.ORCID https://orcid.org/0000-0002-2498-1697
Kian TorabiardakaniDepartment of Anesthesia McMaster University Hamilton Ontario Canada.ORCID https://orcid.org/0009-0001-3520-245X
Gonzalo Bravo-SotoDepartment of Health Research Methods, Evidence, and Impact McMaster University Hamilton Ontario Canada.
Daniela Montalva-RomeroDepartment of Health Research Methods, Evidence, and Impact McMaster University Hamilton Ontario Canada.
Rachel J CoubanMichael G. DeGroote National Pain Center McMaster University Hamilton Ontario Canada.
Lynn CooperMichael G. DeGroote National Pain Center McMaster University Hamilton Ontario Canada.
Stacey RitzDepartment of Pathology & Molecular Medicine McMaster University Hamilton Ontario Canada.ORCID https://orcid.org/0009-0008-6192-182X
Jaris SwidrovichLeslie Dan Faculty of Pharmacy University of Toronto Toronto Ontario Canada.
Ivan D FlorezDepartment of Pediatrics University of Antioquia Medellin Colombia.
Vivian WelchBruyère Health Research Institute University of Ottawa Ottawa Ontario Canada.
Gordon H GuyattDepartment of Health Research Methods, Evidence, and Impact McMaster University Hamilton Ontario Canada.
Holger J SchünemannDepartment of Health Research Methods, Evidence, and Impact McMaster University Hamilton Ontario Canada.ORCID https://orcid.org/0000-0003-3211-8479
Jason W BusseDepartment of Health Research Methods, Evidence, and Impact McMaster University Hamilton Ontario Canada.
on behalf of the Chronic Pain RecMap Collaborative

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Chronic pain affects 1 in 5 adults and children globally; however, management remains highly variable and low value care is common. Inconsistent recommendations among clinical practice guidelines for management of chronic pain contribute to suboptimal patient management. We will develop and disseminate a living digital chronic pain recommendation map (e-Chronic Pain RecMap) to identify trustworthy recommendations in three high priority areas, (1) opioids, (2) cannabis for medical purposes, and (3) spine-related interventional procedures for chronic pain. Methods: The project comprises three phases. A planning phase to engage a diverse group of interest holders to co-design a team structure with our knowledge users to ensure an efficient and effective workflow. Through a search of electronic databases and a manual search of international websites, a development phase to systematically identify relevant guidelines published in any language since 2019. In this development phase, we will update our searches every 6 months. Also, we will appraise the reporting quality of eligible guidelines using the AGREE-II instrument, followed by appraisal of recommendation-level quality using AGREE-REX for guidelines meeting a defined threshold. In a next step, we will extract data from guidelines including relevant equity information using infrastructure in GRADEPro, and explore divergence and compare recommendations answering the same guideline question. Lastly, we will develop plain language summaries of trustworthy recommendations and decision aids to support patient-physician decision making, and translate the platform to French, Spanish, and Mandarin. Finally, a mobilization phase in which, with our interest holders, we will co-create strategies to disseminate the RecMap to relevant target users. Discussion: The Chronic Pain RecMap will enhance use of trustworthy guideline recommendations by people living with chronic pain, clinicians, and decision makers. Successful uptake will optimize evidence-based pain management.

Identifiers

PMID42740756
PMCPMC13563377

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.