ArticleJournal of research in pharmacy practice2026
Healing or Harming? Navigating Resistance and Rationality in Diabetic Foot Ulcer Antibiotic Therapy: A Retrospective Observational Study.
Article in Journal of research in pharmacy practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Diabetic foot ulcers (DFUs) represent a major complication in patients with diabetes mellitus, resulting in reduced quality of life, frequent hospitalizations, and increased healthcare costs. Our study analyzed the clinical records of 200 patients with DFU selected from a pool of medical records from a tertiary care hospital in India. Our study assessed patterns of drug prescription, determined pathogen profiles and antimicrobial susceptibility, evaluated economic burden, and identified the prevalence and severity of drug-drug interactions (DDIs) among patients with DFUs. Antibiotics were the most commonly prescribed drugs (18.5%) with the highest incidence of serious DDIs (28.5%). These results underscore the importance of optimizing antibiotic stewardship and rational prescribing practices to improve clinical outcomes.
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