Evidence map›Paper›PMID 42740723›Full record

ReviewAvicenna journal of phytomedicine

Impact of flavonoid-rich herbal medicines on idiopathic heavy menstrual bleeding: A systematic review and meta-analysis of randomized controlled trials.

Marzieh Qaraaty, Ayesheh Enayati, Maedeh Rezghi, Abdolhalim Rajabi, Mojgan Tansaz, Masoud Mohammadi, Amirhossein Sahebkar

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Avicenna journal of phytomedicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Marzieh QaraatyTraditional Medicine and Materia Medica Research Center and Department of Traditional Medicine, School of Traditional Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Ayesheh EnayatiIschemic Disorders Research Center, Golestan University of Medical Sciences, Gorgan, Iran.
Maedeh RezghiTraditional Medicine and History of Medical Sciences Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.
Abdolhalim RajabiHealth Management and Social Development Research Center, Faculty of Health, Golestan University of Medical Sciences, Gorgan, Iran.
Mojgan TansazTraditional Medicine and Materia Medica Research Center and Department of Traditional Medicine, School of Traditional Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Masoud MohammadiGolestan Research Center of Gastroenterology and Hepatology, Golestan University of Medical Sciences, Gorgan, Iran.
Amirhossein SahebkarApplied Biomedical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Persian medicine has recommended flavonoid-rich plants for idiopathic heavy menstrual bleeding (HMB), highlighting their blood-reducing and antioxidant properties in menorrhagia. We aimed to explore the potential of flavonoid-rich plants as a safe and effective therapy for HMB. Materials and Methods: A systematic search was conducted on 10 databases from inception to July 11, 2023. Randomized controlled trials (RCTs) reporting the use of Persian medicine-recommended plants for idiopathic HMB were included. Outcome measures included the pictorial blood assessment chart (PBAC), duration of bleeding, quality of life, and hemoglobin levels. Results: A total of 12 RCTs involving 425 participants were included in the analysis. The results indicated the potential benefits of plants in terms of PBAC, duration of bleeding, and quality of life. Furthermore, these plants were found to cause a slight statistically significant increase in hemoglobin levels. Conclusion: This study provides valuable insights into the use of the Persian medicine-recommended flavonoid-rich plants for idiopathic HMB. It suggests that flavonoid-rich plants based on Persian medicine may be effective and safe options for idiopathic HMB.

Indexed as

Herbal MedicinesIdiopathic heavy menstrual bleedingMenorrhagiaMeta-AnalysisPersian medicineSystematic review

Identifiers

PMID42740723
PMCPMC13120872

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.