Evidence map›Paper›PMID 42740711›Full record

ArticleExperimental physiology2026

Multi-omics analysis of ion channels expressed by chicken embryo vestibular type I and type II hair cells.

Giulia Cheli, Roberta Giunta, Francesca Stella, Eleonora Guidi, Umberto Laforenza, Mariarosa Polimeni, Giancarlo Russo, Francesca Borgo, Lazarevic Dejan, Sergio Masetto

Abstract read
In one paragraph

Article in Experimental physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Giulia Cheli *Department of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy.ORCID https://orcid.org/0000-0002-2024-8594
Roberta Giunta *Department of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy.
Francesca StellaDepartment of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy.
Eleonora GuidiCenter for Omics Sciences, IRCCS San Raffaele Institute, Milan, Italy.
Umberto LaforenzaDepartment of Molecular Medicine, University of Pavia, Pavia, Italy.
Mariarosa PolimeniDepartment of Public Health, Experimental and Forensic Medicine, University of Pavia, Pavia, Italy.
Giancarlo RussoDepartment of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy.
Francesca BorgoCenter for Omics Sciences, IRCCS San Raffaele Institute, Milan, Italy.
Lazarevic DejanCenter for Omics Sciences, IRCCS San Raffaele Institute, Milan, Italy.
Sergio MasettoDepartment of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy.ORCID https://orcid.org/0000-0003-2955-8430

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Balance and gaze rely on the rapid and accurate detection and signalling of head movements by vestibular type I and type II hair cells. Signal transduction and transmission involve several types of ion channels, which are acquired progressively during hair cell differentiation and whose identity is known only in part. In the present study, we adopted a multi-omics approach to identify the molecular nature of ion channels expressed by chicken vestibular hair cells between embryonic day 15 and embryonic day 21, the day of hatching, when both type I and II hair cells appear functionally mature. Type I hair cells are characterized by the expression of a low-voltage-activated outward rectifying K

Indexed as

Hair Cells, VestibularIon ChannelsAnimalsChick EmbryoChickensMultiomicsIon Channelshair cellion channelpatch clamppatch‐sequencingtranscriptomicsvestibular hair cell

Identifiers

PMID42740711
PMCPMC13576476

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.