Evidence map›Paper›PMID 42740702›Full record

ArticleThe Plant journal : for cell and molecular biology2026

An atypical EF-hand domain containing resistance protein SRC4 boosts plant immunity in a calcium-enhanced manner.

Zikai Zhou, Di Miao, Jie Zhao, Yuxi Zhou, Ting Yan, Niu Niu, Zhuo Bao, Fangjiao Lv, Lu Liu, Ning Xu and 3 more

Abstract read
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In one paragraph

Article in The Plant journal : for cell and molecular biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Zikai ZhouKey Laboratory of Forage and Endemic Crop Biology, Ministry of Education, School of Life Sciences, Inner Mongolia University, Hohhot, 010070, China.ORCID https://orcid.org/0000-0002-1759-1527
Di MiaoKey Laboratory of Forage and Endemic Crop Biology, Ministry of Education, School of Life Sciences, Inner Mongolia University, Hohhot, 010070, China.
Jie ZhaoState Key Laboratory of Agricultural and Forestry Biosecurity, MOA Key Lab of Pest Monitoring and Green Management, College of Plant Protection, China Agricultural University, Beijing, 100193, China.
Yuxi ZhouKey Laboratory of Forage and Endemic Crop Biology, Ministry of Education, School of Life Sciences, Inner Mongolia University, Hohhot, 010070, China.
Ting YanKey Laboratory of State Forestry and Grassland Administration on Sandy Land Biological Resources Conservation and Cultivation, Inner Mongolia Academy of Forestry, Hohhot, 010010, China.
Niu NiuKey Laboratory of Forage and Endemic Crop Biology, Ministry of Education, School of Life Sciences, Inner Mongolia University, Hohhot, 010070, China.
Zhuo BaoKey Laboratory of Forage and Endemic Crop Biology, Ministry of Education, School of Life Sciences, Inner Mongolia University, Hohhot, 010070, China.
Fangjiao LvState Key Laboratory of Agricultural and Forestry Biosecurity, MOA Key Lab of Pest Monitoring and Green Management, College of Plant Protection, China Agricultural University, Beijing, 100193, China.
Lu LiuState Key Laboratory of Agricultural and Forestry Biosecurity, MOA Key Lab of Pest Monitoring and Green Management, College of Plant Protection, China Agricultural University, Beijing, 100193, China.
Ning XuState Key Laboratory of Agricultural and Forestry Biosecurity, MOA Key Lab of Pest Monitoring and Green Management, College of Plant Protection, China Agricultural University, Beijing, 100193, China.ORCID https://orcid.org/0000-0002-8704-1811
Fang YanKey Laboratory of Forage and Endemic Crop Biology, Ministry of Education, School of Life Sciences, Inner Mongolia University, Hohhot, 010070, China.
Jun LiuState Key Laboratory of Agricultural and Forestry Biosecurity, MOA Key Lab of Pest Monitoring and Green Management, College of Plant Protection, China Agricultural University, Beijing, 100193, China.
Hada WuriyanghanKey Laboratory of Forage and Endemic Crop Biology, Ministry of Education, School of Life Sciences, Inner Mongolia University, Hohhot, 010070, China.ORCID https://orcid.org/0000-0002-2762-0926

Funding

Inner Mongolia University Research Platform Open Fund HECB20240F04Innovative Team Development Project for Higher Education of Inner Mongolia 21400-231507Natural Science Foundation of Inner Mongolia 2024ZD20Science and Technology Program of Inner Mongolia 2020GG0045
6 · The paper itself

Abstract

The typical nucleotide-binding leucine-rich repeat (NLR) proteins, such as TIR-NBS-LRR (TNL) and CC-NBS-LRR (CNL), are known to be engaged in effector-triggered immunity (ETI). However, several atypical resistance (R) proteins with truncated NLR domains or with nonclassical domains are emerging to be key regulators in plant immunity. SMV resistance cluster 4 (SRC4) is an atypical NLR protein in soybean, distinguished by an N-terminal Domain (NTD)-TIR-shortened NBS oligomerization region (SNOR)-EF-hand (EFh) domain architecture. SRC4 lacks both NBS and LRR domains but retains basal antiviral activity through its TIR-SNOR region, with SNOR contributing to TIR-dependent antiviral activity and SRC4 self-association. The EFh domain recognizes coat protein (CP) of soybean mosaic virus (SMV) and serves as a Ca

Indexed as

CalciumGlycine maxPlant DiseasesPlant ImmunityPlant ProteinsDisease ResistanceEF Hand MotifsGene Expression Regulation, PlantPlants, Genetically ModifiedPotyvirusCalciumPlant Proteinscalcium ionEFh domainplant immunitySMV resistance cluster 4soybean mosaic virus

Identifiers

PMID42740702
PMCPMC13575729

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.