ArticleMedical physics2026
Quantitative SPECT imaging of
Shixian Du, Kondapa Naidu Bobba, Robin Peter, Grant T Gullberg, Robert R Flavell, Javier Caravaca, Youngho Seo
Abstract read
In one paragraphArticle in Medical physics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
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0citing papers in PubMed
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What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
7 authors.
Shixian DuDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, California, USA.
Kondapa Naidu BobbaDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, California, USA.
Robin PeterDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, California, USA.
Grant T GullbergDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, California, USA.
Robert R FlavellDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, California, USA.
Javier CaravacaDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, California, USA.
Youngho SeoDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, California, USA.
Funding
Translational InformaticsP30CA082103 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Alan Ashworth · 1999 to 2026
$209.7MA high sensitivity gamma camera using a combination of Compton reconstruction and source proximity for in-vivo imaging of Ac-225R01EB032324 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CARAVACA, JAVIER · 2022 to 2025
$3.7MSystematic evaluation of toxicity and therapeutic efficacy in CD46 directed radioligand therapyR01CA279203 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Robert Richard Flavell, Youngho Seo · 2023 to 2026
$2.6MEnergy-independent single photon molecular imaging technologyR01EB026331 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CUI, YONGGANG, SEO, YOUNGHO · 2018 to 2022
$2.6MHigh-throughput microPET/CT at UCSF Preclinical Imaging CoreS10OD034286 · OD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SEO, YOUNGHO · 2023 to 2023
$662kDOD W81XWH2110792NCI NIH HHS P30 CA082103NCI NIH HHS P30CA082103NCI NIH HHS R01 CA279203NCI NIH HHS R01CA279203NIBIB NIH HHS R01 EB026331NIBIB NIH HHS R01EB026331NIBIB NIH HHS R01 EB032324NIBIB NIH HHS R01EB032324NIH HHS S10 OD034286NIH HHS S10OD034286
6 · The paper itselfAbstract
backgroundTargeted alpha therapy (TAT) using actinium-225 ( PURPOSE: This study aims to assess the feasibility and accuracy of quantitative in vivo SPECT/CT imaging for
methodsA state-of-the-art commercial preclinical SPECT/CT scanner was used to image healthy nude mice in vivo and ex vivo after injection of unlabeled
resultsIn vivo SPECT/CT images clearly showed abundant liver uptake, and significant kidney uptake was also observed in 440 keV images for
conclusionsWe demonstrated the ability to image
Indexed as
ActiniumSingle Photon Emission Computed Tomography Computed TomographyTomography, Emission-Computed, Single-PhotonAnimalsImage Processing, Computer-AssistedMiceMice, NudePhantoms, ImagingActiniumActinium-225actinium‐225quantitative imagingSPECT imaging
Identifiers
PMID42740381
PMCPMC13575294
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