Evidence map›Paper›PMID 42740357›Full record

ReviewThe American journal of case reports2026

A Case of Pneumocephalus on Valsalva Maneuver: A Case Report and Literature Review.

Bouchra Chergui, Julien Flament, Nicolas Mulquin, Céline Couvreur

Abstract readCase ReportsReview
In one paragraph

Review in The American journal of case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Bouchra CherguiEmergency Department, CHU (Centre Hospitalier Universitaire) UCLouvain (Université catholique de Louvain) Namur-Godinne, Yvoir, Belgium.
Julien FlamentEmergency Department, CHU (Centre Hospitalier Universitaire) de Charleroi-Chimay, Charleroi, Belgium.
Nicolas MulquinDepartment of Radiology, CHU (Centre Hospitalier Universitaire) UCLouvain (Université catholique de Louvain) Namur-Godinne, Yvoir, Belgium.ORCID 0000-0002-1298-1411
Céline CouvreurEmergency Department, CHU (Centre Hospitalier Universitaire) UCLouvain (Université catholique de Louvain) Namur-Godinne, Yvoir, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND Pneumocephalus is defined as the presence of air within the cranial cavity. Spontaneous onset is rare, with most cases arising secondary to head trauma or surgical procedures. The most common symptom is headache, a frequent concern in the emergency department, with a broad differential diagnosis. The diagnosis is based on a simple brain computed tomography (CT), while the etiological assessment involves magnetic resonance imaging (MRI) and consultation with otorhinolaryngologists. Most cases of pneumocephalus can be managed conservatively; however, some require urgent surgical intervention. CASE REPORT We report the case of a 45-year-old woman with no history of recent trauma or neurosurgical procedures who developed a sudden-onset occipital headache following a Valsalva maneuver. The pain worsened with head movement. Neurological and otorhinolaryngological examinations were unremarkable. Brain CT revealed a small, isolated pneumocephalus localized to the posterior fossa. No anatomical defect was identified on CT and MRI. The patient was managed conservatively. Her symptoms progressively resolved, and follow-up imaging demonstrated spontaneous resorption of the intracranial air. The favorable course suggests spontaneous closure of a potentially Valsalva-induced intracranial sinus cavity. CONCLUSIONS This case highlights the importance of neuroimaging in patients presenting with atypical headaches in the emergency department. Despite its rarity, pneumocephalus remains an underrecognized condition in emergency medicine. In addition to describing an unusual presentation, this report includes a review of previously published cases of Valsalva-induced spontaneous pneumocephalus and contributes a further example to the limited literature on this subject.

Indexed as

PneumocephalusValsalva ManeuverDiagnosis, DifferentialFemaleHeadacheHumansMagnetic Resonance ImagingMiddle AgedTomography, X-Ray Computed

Identifiers

PMID42740357
PMCPMC13592138

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.