Evidence map›Paper›PMID 42740281›Full record

ArticleSensors (Basel, Switzerland)2026

GMoE-AD: Generalized Hyperspectral Anomaly Detection via Mixture-of-Experts and Domain-Invariant Learning.

Mazharul Hossain, Aaron Robinson, Chrysanthe Preza, Lan Wang

Abstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Mazharul HossainComputer Science Department, The University of Memphis, Memphis, TN 38152, USA.ORCID 0000-0002-7470-6140
Aaron RobinsonElectrical and Computer Engineering Department, The University of Memphis, Memphis, TN 38152, USA.
Chrysanthe PrezaElectrical and Computer Engineering Department, The University of Memphis, Memphis, TN 38152, USA.ORCID 0000-0002-7733-117X
Lan WangComputer Science Department, The University of Memphis, Memphis, TN 38152, USA.ORCID 0000-0001-7925-7957

Funding

NTP INFORMATION SYSTEMS SUPPORT27305C0011 · NIEHS · Z-TECH CORPORATION · 2007 to 2009
$4.3M
PROVIDE RABBITS, RATS, MICE, HAMSTERS, GERBILS, GUINEA PIGS27307C0011 · NIEHS · PI BOLEN, WAYNE · 2007 to 2007
$500k
DEVCOM Army Research Laboratory W911QX24C0011NIEHS NIH HHS 27305C0011NIEHS NIH HHS 27307C0011NIEHS NIH HHS 27398C0011
6 · The paper itself

Abstract

Hyperspectral (HS) sensing provides detailed high-dimensional spectral data to identify subtle anomalies and material variations in complex scenes. HS anomaly detection (HS-AD) aims to identify small, spectrally distinct objects or materials in HS imagery without prior target information. However, most HS-AD methods assume that the training and test data are drawn from the same distribution (single-domain). This assumption is often violated in operational sensing because of differences in sensor characteristics, scene composition, atmospheric conditions, and acquisition geometry. To address this challenge, we propose Generalized MoE-AD (GMoE-AD), a neural Mixture-of-Experts (MoE) architecture for robust cross-domain hyperspectral anomaly detection. The framework fuses the outputs of six unsupervised base detectors with representations from a pretrained HS foundation model, combines four neural experts through learned top-2 routing, and applies gradient-reversal-based domain-adversarial training to improve robustness under distribution shifts. A drift-aware test-time adaptation (DTA) variant is evaluated separately. We evaluate GMoE-AD on six public real-world HS benchmark datasets-San-Diego, Salinas, HYDICE-Urban, ABU-Airport, ABU-Beach, and ABU-Urban-and one private Arizona dataset comprising 22 images acquired by four different sensors. Under all-domain training, the model uses the training portions of all seven datasets and is evaluated without access to domain identity or dataset-specific information. GMoE-AD achieves an average ROC-AUC of 0.943, PR-AUC of 0.623, and F1-macro of 0.821 in this setting. In a leave-one-dataset-out (LODO) evaluation, where the target dataset is completely unseen during training, the model maintains an average ROC-AUC of 0.910 and F1-macro of 0.773. The optional DTA variant increases mean ROC-AUC from 0.938 to 0.953 but reduces F1-macro from 0.822 to 0.815, indicating a metric- and dataset-dependent adaptation trade-off. These results suggest that combining neural expert routing, transfer learning, and domain-adversarial representation learning improves robustness across heterogeneous HS datasets and provides a unified approach to anomaly detection in high-dimensional sensor data, supporting deployment in real-world hyperspectral applications where training and deployment conditions differ.

Indexed as

cross-domain learningdomain adaptationdomain generalizationhyperspectral anomaly detectionmixture of expertstransfer learning

Identifiers

PMID42740281
PMCPMC13568319

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.