Evidence map›Paper›PMID 42739371›Full record

ReviewPlants (Basel, Switzerland)2026

Evaluating Causal Claims in Plant Developmental Metabolism: A When-Where-How Framework.

Xiangfei Cheng, Yanan Zhao, Leidi Liu, Yaning Li, Ruohang Zhao, Zhiyao Yang, Xinci Hao, Zhongling Yang, Chengde Yu, Chengming Fan and 1 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Plants (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Xiangfei ChengCenter for Molecular Interactions and Translational Applications, School of Life Sciences, Henan University, Kaifeng 475004, China.
Yanan ZhaoCenter for Molecular Interactions and Translational Applications, School of Life Sciences, Henan University, Kaifeng 475004, China.
Leidi LiuCenter for Molecular Interactions and Translational Applications, School of Life Sciences, Henan University, Kaifeng 475004, China.ORCID 0009-0001-7548-210X
Yaning LiCenter for Molecular Interactions and Translational Applications, School of Life Sciences, Henan University, Kaifeng 475004, China.
Ruohang ZhaoCenter for Molecular Interactions and Translational Applications, School of Life Sciences, Henan University, Kaifeng 475004, China.
Zhiyao YangCenter for Molecular Interactions and Translational Applications, School of Life Sciences, Henan University, Kaifeng 475004, China.
Xinci HaoCenter for Molecular Interactions and Translational Applications, School of Life Sciences, Henan University, Kaifeng 475004, China.
Zhongling YangInternational Joint Research Laboratory for Global Change Ecology, Laboratory of Biodiversity Conservation and Ecological Restoration, School of Life Sciences, Henan University, Kaifeng 475004, China.ORCID 0000-0001-6346-1582
Chengde YuCenter for Molecular Interactions and Translational Applications, School of Life Sciences, Henan University, Kaifeng 475004, China.
Chengming FanState Key Laboratory of Seed Innovation, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China.ORCID 0000-0002-1352-8301
Zhifang LiCenter for Molecular Interactions and Translational Applications, School of Life Sciences, Henan University, Kaifeng 475004, China.

Funding

Ministry of Science and Technology of the People's Republic of China 2021YFD2200103National Natural Science Foundation of China U21A20213
6 · The paper itself

Abstract

Metabolic changes are often described as drivers of plant development even when the evidence establishes only association or a permissive requirement. This review separates biological role from causal status and evaluates claims across seven dimensions: association, necessity, localization, transport, rescue and mediation, sufficiency, and quantitative-threshold testing. We apply a when-where-how framework to four cases. Perturbations of T6P, SnRK1, and TOR support T6P-dependent kinase regulation as a mediator of lateral-root development and are consistent with a context-dependent candidate gate, but its window and threshold remain unresolved. Circadian regulation of

Indexed as

AI-assisted breedingcausal inferencedevelopmental competencemetabolic statephloem transportSnRK1–TOR signalingsource–sink allocationspatial metabolismspecialized metabolismtrehalose 6-phosphate

Identifiers

PMID42739371
PMCPMC13567439

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.