Evidence map›Paper›PMID 42738921›Full record

ReviewNutrients2026

Kava (

Jason Krehl, Jessica Nissi Mamallapalli, Chengguo Xing, Oliver Grundmann

Abstract readReview
In one paragraph

Review in Nutrients, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jason KrehlDepartment of Medicinal Chemistry, College of Pharmacy, University of Florida, Gainesville, FL 32611, USA.
Jessica Nissi MamallapalliDepartment of Medicinal Chemistry, College of Pharmacy, University of Florida, Gainesville, FL 32611, USA.ORCID 0000-0003-2879-129X
Chengguo XingDepartment of Medicinal Chemistry, College of Pharmacy, University of Florida, Gainesville, FL 32611, USA.ORCID 0000-0002-4266-6236
Oliver GrundmannDepartment of Medicinal Chemistry, College of Pharmacy, University of Florida, Gainesville, FL 32611, USA.ORCID 0000-0003-2302-8949

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Substance use disorders (SUDs) remain a major public health concern and contribute substantially to compromised quality of life, mortality, and healthcare burden. In the United States alone, millions of individuals are affected by alcohol use disorder (AUD), tobacco use disorder (TUD), and opioid use disorder (OUD), with many cases complicated by co-existing anxiety and stress-related disorders.

Indexed as

KavaPlant ExtractsSubstance-Related DisordersAnimalsAnti-Anxiety AgentsHumansPhytotherapySignal TransductionAnti-Anxiety AgentsPlant Extractsadjunctive therapyalcohol use disorderanxietykavakavalactonesPiper methysticumstresssubstance use disorder

Identifiers

PMID42738921
PMCPMC13567056

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.