Evidence map›Paper›PMID 42738900›Full record

ArticleCells2026

A Truncated Serpin D1 Variant Regulates Adseverin-Dependent Actin Severing and Is Required for Osteoclastogenesis.

Yongqiang Wang, Chenfan Ji, Andrew Y Wang, Masoud Norouzi, Isabel Ding, Michael Glogauer, Mark Abovsky, Igor Jurisica, Christopher A McCulloch

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yongqiang WangFaculty of Dentistry, University of Toronto, Toronto, ON M5G 1G6, Canada.ORCID 0009-0002-2629-8979
Chenfan JiFaculty of Dentistry, University of Toronto, Toronto, ON M5G 1G6, Canada.
Andrew Y WangFaculty of Dentistry, University of Toronto, Toronto, ON M5G 1G6, Canada.ORCID 0000-0001-9123-8214
Masoud NorouziFaculty of Dentistry, University of Toronto, Toronto, ON M5G 1G6, Canada.
Isabel DingFaculty of Dentistry, University of Toronto, Toronto, ON M5G 1G6, Canada.
Michael GlogauerFaculty of Dentistry, University of Toronto, Toronto, ON M5G 1G6, Canada.ORCID 0000-0002-6248-5977
Mark AbovskyOsteoarthritis Research Program, Division of Orthopedic Surgery, Schroeder Arthritis Institute and Data Science Discovery Centre for Chronic Diseases, Krembil Research Institute, University Health Network, Toronto, ON M5T 0S8, Canada.
Igor JurisicaFaculty of Dentistry, University of Toronto, Toronto, ON M5G 1G6, Canada.
Christopher A McCullochFaculty of Dentistry, University of Toronto, Toronto, ON M5G 1G6, Canada.ORCID 0000-0002-3535-8593

Funding

CIHR MOP-142250
6 · The paper itself

Abstract

Adseverin is a Ca

Indexed as

ActinsOsteoclastsOsteogenesisSerpinsAnimalsCalciumCell DifferentiationHumansMiceProtein IsoformsRAW 264.7 CellsActinsCalciumProtein IsoformsSerpinsactin filamentsactin severingcell fusionsignaling

Identifiers

PMID42738900
PMCPMC13565667

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.