The Dual Face of Gingival Mesenchymal Stem Cell Paracrine Signalling in Oral Squamous Cell Carcinoma: A Pro-Tumour Transcriptional Programme and a Hypothesis-Generating Drug-Repurposing Screen.

Abdullah Alqarni, Jagadish Hosmani, Saeed Arem, Hussain Almubarak, Hassan Ahmed Assiri, Rayan Mohammedfarooq Meer, Shankargouda Patil

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In one paragraph

Article in Cells, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Abdullah AlqarniDepartment of Oral Diagnosis, Oral Biology & Periodontology, College of Dentistry, King Khalid University, Abha 61421, Saudi Arabia.ORCID 0000-0003-0564-0616

Jagadish HosmaniDepartment of Oral Diagnosis, Oral Biology & Periodontology, College of Dentistry, King Khalid University, Abha 61421, Saudi Arabia.ORCID 0000-0003-3579-0906

Saeed AremDepartment of Diagnostic Science and Oral Biology, College of Dentistry, King Khalid University, P.O. Box 960, Abha 61421, Saudi Arabia.ORCID 0000-0001-7013-2808

Hussain AlmubarakDepartment of Oral Diagnosis, Oral Biology & Periodontology, College of Dentistry, King Khalid University, Abha 61421, Saudi Arabia.

Hassan Ahmed AssiriDepartment of Oral Diagnosis, Oral Biology & Periodontology, College of Dentistry, King Khalid University, Abha 61421, Saudi Arabia.

Rayan Mohammedfarooq MeerDepartment of Preventive Dental Sciences, College of Dentistry, Taibah University, Madinah 42353, Saudi Arabia.ORCID 0009-0007-3080-2775

Shankargouda PatilCollege of Dental Medicine, Roseman University of Health Sciences, South Jordan, UT 84095, USA.ORCID 0000-0001-7246-5497

Funding

King Khalid University R.G.P. 1/297/46

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Carcinoma, Squamous CellGingivaMesenchymal Stem CellsMouth NeoplasmsParacrine CommunicationTranscription, GeneticApoptosisCell MovementCell ProliferationCulture Media, ConditionedGene Expression Regulation, NeoplasticHumansCulture Media, Conditionedcell–cell communicationcircular analysisdrug repurposinggingival mesenchymal stem cellsoral squamous cell carcinomaparacrine signallingproteogenomicssingle-cell transcriptomicsspatial transcriptomicsTCGA-HNSCtumour microenvironment

Identifiers

PMID42738835

DOI10.3390/cells15171538

PMCPMC13565543

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.