Evidence map›Paper›PMID 42738823›Full record

ArticleCells2026

Pulsed Electromagnetic Fields Modulate Inflammatory and Tenogenic Responses in Human Tenocytes: Insights from Acute and Prolonged Inflammation Models.

Michela Maria Taiana, Paola De Luca, Giulio Grieco, Enrico Ragni, Simona Salati, Antonio Marmotti, Valerio Pascale, Laura de Girolamo

Abstract read
In one paragraph

Article in Cells, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Michela Maria TaianaIRCCS Ospedale Galeazzi Sant'Ambrogio, Laboratorio di Biotecnologie Applicate all'Ortopedia, 20157 Milan, Italy.ORCID 0000-0001-8257-8831
Paola De LucaIRCCS Ospedale Galeazzi Sant'Ambrogio, Laboratorio di Biotecnologie Applicate all'Ortopedia, 20157 Milan, Italy.ORCID 0000-0001-9810-8818
Giulio GriecoIRCCS Ospedale Galeazzi Sant'Ambrogio, Laboratorio di Biotecnologie Applicate all'Ortopedia, 20157 Milan, Italy.
Enrico RagniIRCCS Ospedale Galeazzi Sant'Ambrogio, Laboratorio di Biotecnologie Applicate all'Ortopedia, 20157 Milan, Italy.
Simona SalatiMedical Division, IGEA, 41012 Carpi, Italy.ORCID 0000-0002-8072-1128
Antonio MarmottiDepartment of Orthopaedics and Traumatology, University of Turin, 10100 Turin, Italy.ORCID 0000-0002-1683-6094
Valerio PascaleIRCCS Ospedale Galeazzi Sant'Ambrogio, Ortopedia Clinicizzata, 20157 Milan, Italy.
Laura de GirolamoIRCCS Ospedale Galeazzi Sant'Ambrogio, Laboratorio di Biotecnologie Applicate all'Ortopedia, 20157 Milan, Italy.ORCID 0000-0002-9979-3092

Funding

Ministry of Health, Italy CUP C43C22002370001
6 · The paper itself

Abstract

Tendinopathy is a prevalent musculoskeletal condition characterised by chronic inflammatory and degenerative changes. Pulsed electromagnetic fields (PEMFs) represent a promising biophysical therapeutic modality, yet their effects across different inflammatory states of tendinopathy remain poorly characterised. To evaluate PEMF biological effects on human tenocytes, three in vitro models differing in IL-1β dose and duration were tested: acute low-dose (0.1 ng/mL, 96 h), acute high-dose (1 ng/mL, 96 h), and prolonged (0.1 ng/mL, 9 days). At the transcriptional level, PEMFs significantly reduced

Indexed as

Electromagnetic FieldsInflammationModels, BiologicalTendinopathyTenocytesCell ProliferationChemokine CCL2HumansInterleukin-1betaWound HealingChemokine CCL2Interleukin-1betahuman tenocytesinflammatory modelsInterleukin-1β (IL-1β)pulsed electromagnetic fields (PEMFs)tendinopathy

Identifiers

PMID42738823
PMCPMC13565733

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.