Evidence map›Paper›PMID 42738792›Full record

ArticleMolecules (Basel, Switzerland)2026

Fungal Melanins as Potential Reactive Oxygen Species-Scavenging Neuroprotective Agents.

Vy D A Nguyen, Yen T H Tran, Debby Mangelings, Yvan Vander Heyden, Ann Van Eeckhaut, Hanh T M Tran

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Vy D A NguyenApplied Microbiology Laboratory, School of Biotechnology, International University-VNU HCM, Linh Xuan Ward, Ho Chi Minh City 71309, Vietnam.
Yen T H TranApplied Microbiology Laboratory, School of Biotechnology, International University-VNU HCM, Linh Xuan Ward, Ho Chi Minh City 71309, Vietnam.ORCID 0000-0003-3042-0738
Debby MangelingsResearch Group Analytical Chemistry, Applied Chemometrics and Molecular Modelling, Vrije Universiteit Brussel (VUB), Laarbeeklaan 103, 1090 Brussels, Belgium.
Yvan Vander HeydenResearch Group Analytical Chemistry, Applied Chemometrics and Molecular Modelling, Vrije Universiteit Brussel (VUB), Laarbeeklaan 103, 1090 Brussels, Belgium.ORCID 0000-0002-7788-9886
Ann Van EeckhautResearch Group Experimental Pharmacology (EFAR), Department of Pharmaceutical Chemistry, Drug Analysis and Drug Information (FASC), Center for Neurosciences (C4N), Vrije Universiteit Brussel (VUB), Laarbeeklaan 103, 1090 Brussels, Belgium.ORCID 0000-0002-1695-7398
Hanh T M TranApplied Microbiology Laboratory, School of Biotechnology, International University-VNU HCM, Linh Xuan Ward, Ho Chi Minh City 71309, Vietnam.

Funding

VLIR-UOS VN2022TEA534A105
6 · The paper itself

Abstract

Oxidative stress is strongly associated with neuronal damage in neurodegenerative diseases, such as Parkinson's disease (PD). Fungal melanins are remarkable free radical scavengers; however, their capacity to protect neurons from reactive oxygen species (ROS)-induced damage remains understudied. This research evaluated the neuroprotective effects of fungal melanins and their arginine-modified counterparts on SH-SY5Y cells against neurotoxins, as well as their impact on ROS levels. Exposure to 0.6 mM H

Indexed as

Free Radical ScavengersFungiMelaninsNeuroprotective AgentsReactive Oxygen SpeciesCell Line, TumorCell SurvivalHumansHydrogen PeroxideOxidative StressFree Radical ScavengersHydrogen PeroxideMelaninsNeuroprotective AgentsReactive Oxygen Species1-methyl-4-phenylpyridinium (MPP+)hydrogen peroxide (H2O2)melanin-producing fungineuroprotectionSH-SY5Y cells

Identifiers

PMID42738792
PMCPMC13567587

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.