Evidence map›Paper›PMID 42738765›Full record

ArticleMolecules (Basel, Switzerland)2026

Novel Caffeine-Assisted Aqueous Extraction Strategy for Enhanced Solubilization of Polycyclic Aromatic Hydrocarbons from Creosote-Treated Waste Wood.

Željka M Nikolić, Nebojša R Radović, Aleksandra M Radulović, Milica P Marčeta Kaninski, Vladimir M Nikolić, Dragana Z Živojinović

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Željka M NikolićInstitute of General and Physical Chemistry, Studentski trg 12/V, 11000 Belgrade, Serbia.ORCID 0000-0002-2922-0256
Nebojša R RadovićFaculty of Chemistry, University of Belgrade, Studentski trg 12-16, 11000 Belgrade, Serbia.ORCID 0000-0002-7587-8569
Aleksandra M RadulovićInstitute of General and Physical Chemistry, Studentski trg 12/V, 11000 Belgrade, Serbia.
Milica P Marčeta KaninskiInstitute of General and Physical Chemistry, Studentski trg 12/V, 11000 Belgrade, Serbia.ORCID 0000-0001-6713-3754
Vladimir M NikolićInstitute of General and Physical Chemistry, Studentski trg 12/V, 11000 Belgrade, Serbia.ORCID 0000-0002-3479-473X
Dragana Z ŽivojinovićFaculty of Technology and Metallurgy, University of Belgrade, Karnegijeva 4, 11000 Belgrade, Serbia.ORCID 0000-0002-7862-3246

Funding

Ministry of Science, Technological Development, and Innovation 451-03-033/2026-03/200051 and 451-03-34/2026-03/200135
6 · The paper itself

Abstract

This study evaluates caffeine-assisted aqueous extraction systems for the enhanced extraction of Σ16 US EPA priority polycyclic aromatic hydrocarbons (PAHs) from waste creosote-infused wood. Aqueous solutions of eight water-soluble organic acids were investigated with and without caffeine to assess its effect on PAH extraction. Caffeine improved extraction across all systems, but the extent of this improvement varied depending on the initial performance of each extraction agent without caffeine. Deionized water exhibited a negligible extraction yield (0.0027%), whereas caffeine addition increased the yield to 1.6886%, corresponding to a 625-fold improvement. Despite substantial differences among agents without caffeine, most caffeine-containing systems achieved similar extraction yields (4.2-5.3%), indicating that caffeine-induced hydrotropic solubilization became the dominant factor governing PAH extraction. Based on the maximum extraction performance achieved in the presence of caffeine, the investigated systems can be ranked as follows: acetic acid-caffeine > citric acid-caffeine > p-TsOH-caffeine ≈ tartaric acid-caffeine ≈ lactic acid-caffeine ≈ formic acid-caffeine > ascorbic acid-caffeine. These findings identify caffeine-assisted aqueous extraction as a promising approach for enhancing PAH extraction from creosote-treated waste wood while reducing reliance on conventional organic solvents in the primary extraction step.

Indexed as

caffeinepolycyclic aromatic hydrocarbonsrailroad tiessolvent extraction

Identifiers

PMID42738765
PMCPMC13566980

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