Comparative Structural Characterisation and In Vitro Bioactivities of Crude and Purified Polysaccharides from Dandelion (

Jingwen Zhang, Fujuan Zhang, Yuxuan Liu, Cuntang Wang, Guojun Du

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Article in Molecules (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 authors.

Jingwen ZhangCollege of Food and Bioengineering, Qiqihar University, Qiqihar 161006, China.

Fujuan ZhangDepartment of Biochemical Engineering, Chaoyang Normal University, Chaoyang 122000, China.

Yuxuan LiuCollege of Food and Bioengineering, Qiqihar University, Qiqihar 161006, China.

Cuntang WangCollege of Food and Bioengineering, Qiqihar University, Qiqihar 161006, China.

Guojun DuCollege of Food and Bioengineering, Qiqihar University, Qiqihar 161006, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The increasing demand for functional products has promoted research on bioactive compounds. Dandelion root polysaccharide (DRP), a key bioactive component of Taraxacum officinale, has anti-inflammatory, antioxidant, hypoglycemic and hypolipidemic activities. This study extracted DRP via microwave-assisted enzymatic extraction (MAEE) to obtain mDRP, and isolated acidic polysaccharide mDRP-1 (7.548 kDa) by column chromatography. HPLC showed that both contain six monosaccharides (Man, Rha, GalA, Glu, Gal, Ara) with different molar ratios. mDRP is heterogeneous (trace protein/nucleic acids, no triple helix, amorphous), while mDRP-1 has a triple-helical, semi-crystalline structure; both have characteristic polysaccharide peaks and pyranose rings, and rough, porous surfaces. mDRP had better thermal stability and significant concentration-dependent in vitro antioxidant and hypoglycaemic effects.

Indexed as

Plant ExtractsPlant RootsPolysaccharidesTaraxacumAntioxidantsChromatography, High Pressure LiquidHypoglycemic AgentsMicrowavesMonosaccharidesAntioxidantsHypoglycemic AgentsMonosaccharidesPlant ExtractsPolysaccharidesantioxidant activityDandelion root polysaccharideshypoglycaemic activitymicrowave-assisted compound enzymatic extractionstructural characterisation

Identifiers

PMID42738627

DOI10.3390/molecules31172966

PMCPMC13567065

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.