Evidence map›Paper›PMID 42738498›Full record

ArticleAnimals : an open access journal from MDPI2026

Comparative Assessment of Cortisol, Leptin, Haptoglobin and Inflammatory Interleukins in Modicana and Holstein Cows During the Peripartum Period.

Federica Arrigo, Maria Rizzo, Giulia Sisia, Claudia Giannetto, Elisabetta Giudice, Giuseppe Piccione, Francesca Arfuso

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Federica ArrigoDepartment of Veterinary Sciences, University of Messina, 98121 Messina, Italy.
Maria RizzoDepartment of Veterinary Sciences, University of Messina, 98121 Messina, Italy.ORCID 0000-0003-4343-8937
Giulia SisiaDepartment of Veterinary Sciences, University of Messina, 98121 Messina, Italy.
Claudia GiannettoDepartment of Veterinary Sciences, University of Messina, 98121 Messina, Italy.ORCID 0000-0003-3049-1181
Elisabetta GiudiceDepartment of Veterinary Sciences, University of Messina, 98121 Messina, Italy.
Giuseppe PiccioneDepartment of Veterinary Sciences, University of Messina, 98121 Messina, Italy.ORCID 0000-0002-4736-1087
Francesca ArfusoDepartment of Veterinary Sciences, University of Messina, 98121 Messina, Italy.ORCID 0000-0001-6139-2691

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Understanding breed-related physiological responses during the peripartum period may contribute to the development of more resilient and sustainable dairy systems. This study compared endocrine and inflammatory responses in a native Sicilian breed, Modicana, and a high-producing cosmopolitan breed, Holstein, during the 15 days before and 15 days after calving. Twenty cows (10 per breed), managed under the same conditions, were monitored for serum cortisol, haptoglobin, leptin, IL-1β, IL-6 and TNF-α. Both breeds showed peripartum changes in cortisol and haptoglobin concentrations (

Indexed as

dairy cowsHolsteinModicananative breedperipartum periodstress

Identifiers

PMID42738498
PMCPMC13565469

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.