Evidence map›Paper›PMID 42738471›Full record

ArticleAnimals : an open access journal from MDPI2026

Dietary Arginine Supplementation Mitigates Heat Stress-Induced Testicular Dysfunction Through Arginine-Related Metabolic Remodeling and Autophagy-Associated Stress Adaptation in a Rongchang Boar Model.

Xiao Lin, Kun Wu, Jingchang Ren, Yong Zhuo, Bin Feng, Lianqiang Che, Zhengfeng Fang, Shengyu Xu, Lun Hua, Guangmang Liu and 4 more

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Xiao LinAnimal Nutrition Institute, Sichuan Agricultural University, Chengdu 611130, China.
Kun WuAnimal Nutrition Institute, Sichuan Agricultural University, Chengdu 611130, China.
Jingchang RenAnimal Nutrition Institute, Sichuan Agricultural University, Chengdu 611130, China.
Yong ZhuoAnimal Nutrition Institute, Sichuan Agricultural University, Chengdu 611130, China.ORCID 0000-0002-8348-4199
Bin FengAnimal Nutrition Institute, Sichuan Agricultural University, Chengdu 611130, China.ORCID 0000-0001-6258-2729
Lianqiang CheAnimal Nutrition Institute, Sichuan Agricultural University, Chengdu 611130, China.
Zhengfeng FangAnimal Nutrition Institute, Sichuan Agricultural University, Chengdu 611130, China.
Shengyu XuAnimal Nutrition Institute, Sichuan Agricultural University, Chengdu 611130, China.ORCID 0000-0002-4415-8542
Lun HuaAnimal Nutrition Institute, Sichuan Agricultural University, Chengdu 611130, China.
Guangmang LiuAnimal Nutrition Institute, Sichuan Agricultural University, Chengdu 611130, China.ORCID 0000-0003-2385-7528
Xiaojun JiangSichuan DaBeiNong Agriculture and Animal Husbandry Technology Co., Ltd., Chengdu 611430, China.
Jian LiAnimal Nutrition Institute, Sichuan Agricultural University, Chengdu 611130, China.
De WuAnimal Nutrition Institute, Sichuan Agricultural University, Chengdu 611130, China.
Yan LinAnimal Nutrition Institute, Sichuan Agricultural University, Chengdu 611130, China.

Funding

National Natural Science Foundation of China 32272911National Natural Science Foundation of China 32573270Sichuan Pig Innovation Team of the National Modern Agricultural Industry Technology System SCSZTD-2024-08Sichuan Province "14th Five-Year" Sichuan Pig Major Science and Technology Project 2021ZDZX0009
6 · The paper itself

Abstract

Heat stress compromises male reproductive function in livestock and other mammals. Arginine is a conditionally essential amino acid involved in metabolic regulation; however, its protective effects on the male reproductive system under heat stress remain unclear. Using a heat-stressed Rongchang boar model, this study aimed to explore the possible mechanism of dietary arginine supplementation on sperm quality and testicular function. Twenty-four Rongchang boars were assigned to three treatments: thermoneutral control (CON), heat-stressed control (HS), or heat-stressed treatment supplemented with 0.8% dietary arginine (HA). Results showed that heat stress reduced feed intake, body weight, sperm viability, sperm concentration, and sperm motion parameters (

Indexed as

arginine metabolismautophagydietary arginineheat stressRongchang boartesticular dysfunction

Identifiers

PMID42738471
PMCPMC13564319

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.