Evidence map›Paper›PMID 42738435›Full record

ArticleAnimals : an open access journal from MDPI2026

Lactobacillus Modulates the Rumen Microbiota and Transcriptome to Enhance Nutrient Digestion in Yaks Fed High-Concentrate Diets During the Cold Season.

Hao Ren, Qian Chen, Majireding Aikelaimuc, Liang Qin, Guangfeng Zhang, Linlin Liu, Jianlei Jia

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hao RenSchool of Life Sciences, Qilu Normal University, Jinan 250200, China.
Qian ChenSchool of Life Sciences, Qilu Normal University, Jinan 250200, China.
Majireding AikelaimucTaxkorgan Tajik Autonomous County Livestock Breeding Center, Kashi 845250, China.
Liang QinZhangqiu Animal Husbandry and Veterinary Science Development Center, Jinan 250200, China.
Guangfeng ZhangZhangqiu Animal Husbandry and Veterinary Science Development Center, Jinan 250200, China.
Linlin LiuZhangqiu Animal Husbandry and Veterinary Science Development Center, Jinan 250200, China.
Jianlei JiaSchool of Life Sciences, Qilu Normal University, Jinan 250200, China.ORCID 0000-0001-5843-1709

Funding

Natural Science Foundation of Shandong Province ZR2023MC164Youth Innovation Team Project Program of Shandong Provincial Education Department 2022KJ137
6 · The paper itself

Abstract

Intensive yak fattening in cold alpine regions requires essential long-term high-concentration feeding, which disrupts rumen microbial homeostasis and causes inefficient digestion of nutrients. Lactobacillus may have probiotic potential for ruminants, yet its regulation of rumen function is poorly understood under high-energy diets. During a 120-day feeding experiment, 120 male Pamir yaks were allocated to four dietary treatments, with LEG and LLG serving as the primary comparison for evaluating 0.02% Lactobacillus supplementation to explore the regulatory effects of Lactobacillus supplementation on the rumen microbiota and host metabolism of yaks during a fattening process based on a concentrate feed diet via phenotypic data (body wight and nutrient digestibility) and multi-omics analyses (rumen microbial sequencing and rumen epithelial transcriptome) in a concentrate-based rearing yak model. The results showed that Lactobacillus intervention reduced OTU (Operational Taxonomic Unit) richness during the early fattening period and subsequently promoted microbial recovery through colonization resistance, which significantly enhanced microbial diversity (

Indexed as

high-concentrate dietlactobacillusmulti-omics integrationPamir yakphenotypic data

Identifiers

PMID42738435
PMCPMC13564310

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.