Evidence map›Paper›PMID 42738410›Full record

ReviewCancers2026

Focused Ultrasound Therapies for Brain, Liver, Prostate, and Breast Cancer Applications: Clinical Evidence and Future Directions.

Nassib Abou Heidar, Daniel Sheeran, Divine Nwafor, Olivia C Sears, Shayan Moosa, Lynn T Dengel, Kirsten Greene, Alan H Matsumoto

Abstract readReview
In one paragraph

Review in Cancers, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nassib Abou HeidarDepartment of Urology, University of Virginia Health, Charlottesville, VA 22908, USA.
Daniel SheeranDepartment of Radiology and Medical Imaging, University of Virginia Health, Charlottesville, VA 22908, USA.ORCID 0000-0003-2952-6834
Divine NwaforDepartment of Neurosurgery, University of Virginia Health, Charlottesville, VA 22908, USA.
Olivia C SearsDepartment of Surgery, University of Virginia Health, Charlottesville, VA 22908, USA.ORCID 0000-0001-9987-7563
Shayan MoosaDepartment of Neurosurgery, University of Virginia Health, Charlottesville, VA 22908, USA.
Lynn T DengelDepartment of Surgery, University of Virginia Health, Charlottesville, VA 22908, USA.
Kirsten GreeneDepartment of Urology, University of Virginia Health, Charlottesville, VA 22908, USA.
Alan H MatsumotoDepartment of Radiology and Medical Imaging, University of Virginia Health, Charlottesville, VA 22908, USA.ORCID 0000-0001-7162-1590

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Focused ultrasound (FUS) is an emerging and evolving minimally invasive therapeutic platform that is helping to redefine the management of malignant diseases. Clinical translation is advancing rapidly, with several completed and ongoing clinical trials demonstrating the safety, feasibility, and early efficacy of FUS in the treatment of cancer. This manuscript provides a synthesis of some of the available clinical data and device platforms being used and evaluates the results from completed and active clinical trials for cancers involving four different solid organs. To stay within the editorial parameters of the invited article, this review will not provide a meta-analysis of clinical trials data and/or the literature but rather highlight some of the currently available clinical evidence and FUS technologies that have been used in the treatment of cancers of the brain, liver, prostate gland, and breast.

Indexed as

blood–brain barrier openingcancer treatmentclinical trialsdrug deliveryfocused ultrasoundHIFUhistotripsyimmunotherapylocoregional therapynoninvasive image-guided therapysonodynamic therapy

Identifiers

PMID42738410
PMCPMC13564846

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.