Evidence map›Paper›PMID 42738409›Full record

ReviewCancers2026

The Immune Landscape of Chondrosarcoma: A Review of Tumor-Related Immune Cells.

Maria T Silvaggio, Christian P Tabler, Sila Basbay, Kurt Weiss, Karen Schoedel, Ines Lohse

Abstract readReview
In one paragraph

Review in Cancers, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Maria T SilvaggioDepartment of Orthopedic Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA 15219, USA.
Christian P TablerDepartment of Orthopedic Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA 15219, USA.
Sila BasbayDepartment of Orthopedic Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA 15219, USA.ORCID 0009-0004-3575-511X
Kurt WeissDepartment of Orthopedic Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA 15219, USA.ORCID 0000-0003-3859-728X
Karen SchoedelDepartment of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.ORCID 0000-0001-5398-8962
Ines LohseDepartment of Orthopedic Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA 15219, USA.ORCID 0000-0002-9979-9400

Funding

UPMC Hillman Cancer Center AcademyR25CA236620 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CHRISTOPHER J. BAKKENIST, David Boone · 2019 to 2026
$2.7M
NCI NIH HHS R25 CA236620NCI NIH HHS R25CA236620Orland Bethel Musculoskeletal Research Center summer program No Grant NumberPittsburgh Cure SarcomaUnited States Department of Defense Resource and Community Development Award
6 · The paper itself

Abstract

Chondrosarcoma (CS) is a rare cancer comprising a heterogeneous group of malignant cartilage-forming tumors. CS is considered a "surgical disease" characterized by high levels of resistance to chemotherapy, radiation therapy, and limited response to immune checkpoint inhibitors. Due to the rarity of the disease and lack of research models, the impact of the CS microenvironment on tumor development and progression remains elusive. Nevertheless, a few recent studies have begun to interpret the composition and function of the CS tumor immune microenvironment (TME), elucidating its contribution to immune evasion and tumor progression. This review summarizes current findings on the immune cell landscape of CS, highlighting key immune cells, their characteristics, and their potential as therapeutic targets.

Indexed as

B-cellscancerchondrosarcomaexpressionmacrophagenatural killerneutrophilT-cellstumor immune microenvironment

Identifiers

PMID42738409
PMCPMC13564600

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.