Evidence map›Paper›PMID 42738341›Full record

ReviewCancers2026

MR-Guided Adaptive Radiotherapy in Lung Cancer: Current Landscape and Future Directions.

Abrahams Ocanto, Macarena Teja, Daniela Gonsalves, Walter Vásquez, Inmaculada Navarro-Domenech, Marta Moreno-Jimenez, Gloria Guardia, Dulce Urias, Scarlet Crespo, Mariana Temes and 7 more

Abstract readReview
In one paragraph

Review in Cancers, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Abrahams OcantoDepartment of Radiation Oncology, San Francisco de Asís University Hospital, GenesisCare, 28002 Madrid, Spain.ORCID 0000-0002-6494-8197
Macarena TejaDepartment of Radiation Oncology, Gregorio Marañón General University Hospital, 28007 Madrid, Spain.ORCID 0009-0004-1719-622X
Daniela GonsalvesDepartment of Radiation Oncology, San Francisco de Asís University Hospital, GenesisCare, 28002 Madrid, Spain.ORCID 0009-0009-7757-7653
Walter VásquezDepartment of Radiation Oncology, Jiménez Díaz University Hospital, 28040 Madrid, Spain.
Inmaculada Navarro-DomenechDepartment of Radiation Oncology, La Paz University Hospital, 28046 Madrid, Spain.ORCID 0000-0001-7347-2461
Marta Moreno-JimenezDepartment of Radiation Oncology, Clínica Universidad de Navarra, 31008 Pamplona, Spain.
Gloria GuardiaDepartment of Radiation Oncology, San Francisco de Asís University Hospital, GenesisCare, 28002 Madrid, Spain.
Dulce UriasDepartment of Radiation Oncology, National Cancer Institute (INCAN), Mexico City 14080, Mexico.
Scarlet CrespoDepartment of Radiation Oncology, Santa Creu i Sant Pau Hospital, 08041 Barcelona, Spain.
Mariana TemesDepartment of Radiation Oncology, 12 de Octubre University Hospital, 28041 Madrid, Spain.
Nicolly HernándezDepartment of Radiation Oncology, Clínica Universidad de Navarra, 31008 Pamplona, Spain.
Suresh SenanDepartment of Radiation Oncology, Amsterdam University Medical Centers, Vrije Universiteit Amsterdam, Cancer Center Amsterdam, 1117 Amsterdam, The Netherlands.ORCID 0000-0003-3995-2204
Drew MoghanakiDepartment of Radiation Oncology, University of California, Los Angeles, CA 90095, USA.
Rosa MoreraDepartment of Radiation Oncology, La Paz University Hospital, 28046 Madrid, Spain.
Ignacio AzinovicDepartment of Radiation Oncology, Clínica Universidad de Navarra, 31008 Pamplona, Spain.
Javier LunaDepartment of Radiation Oncology, Jiménez Díaz University Hospital, 28040 Madrid, Spain.
Felipe CouñagoDepartment of Radiation Oncology, San Francisco de Asís University Hospital, GenesisCare, 28002 Madrid, Spain.ORCID 0000-0001-7233-0234

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Magnetic resonance-guided radiotherapy (MRgRT) delivered with MR-linac technology represents a major advance in lung cancer radiotherapy, enabling daily online adaptive planning based on high-quality soft-tissue visualization, real-time motion assessment, and anatomy-driven treatment personalization. The challenges in lung cancer treatment with conventional radiotherapy delivery due to respiratory motion, inter and intra-fraction anatomical changes make MRgRT capabilities particularly relevant. This narrative review provides an overview of the current state of the art of MR-guided adaptive radiotherapy in lung cancer, focusing on technical foundations, adaptive workflows, and clinical implementation across different disease stages. Key aspects as patient selection, adaptive decision-making, motion management strategies, and integration into routine clinical practice are discussed. Finally, emerging clinical applications and future directions-including adaptive dose personalization and integration of functional imaging-are outlined, highlighting the potential role of MR-linac-based adaptive radiotherapy as a platform for precision radiotherapy in lung cancer.

Indexed as

adaptive radiotherapyimage guidancelung cancermagnetic-resonance linear-accelerator

Identifiers

PMID42738341
PMCPMC13565088

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.