Internal Architecture of a 3D-Printed Ti-6Al-4V Capsule and Preliminary FEM Simulation of Diffusion: CAD-Informed Modeling with Qualitative Micro-CT Characterization.

Katarzyna Kazimierska, Grzegorz Szala, Adam Mazurkiewicz, Mikołaj Wiśniewski, Igor Olszewski

Abstract read

In one paragraph

Article in Materials (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Katarzyna KazimierskaFaculty of Mechatronics, Kazimierz Wielki University, Mikołaja Kopernika 1, 85-074 Bydgoszcz, Poland.ORCID 0000-0002-7098-9622

Grzegorz SzalaFaculty of Mechatronics, Kazimierz Wielki University, Mikołaja Kopernika 1, 85-074 Bydgoszcz, Poland.ORCID 0000-0001-5398-2405

Adam MazurkiewiczFaculty of Mechanical Engineering, Bydgoszcz University of Science and Technology, Al. Prof. S. Kaliskiego 7, 85-796 Bydgoszcz, Poland.ORCID 0000-0002-2886-0040

Mikołaj WiśniewskiAlufasady LCC, Nakielska 247, 85-391 Bydgoszcz, Poland.ORCID 0009-0009-3506-2125

Igor OlszewskiFaculty of Mechatronics, Kazimierz Wielki University, Mikołaja Kopernika 1, 85-074 Bydgoszcz, Poland.ORCID 0009-0005-6362-419X

Funding

Minister of Science (Republic of Poland) RID/SP/0048/2024/01

6 · The paper itself

Abstract

A central challenge in implantable local-delivery systems is to determine how internal device architecture shapes solute transport before drug-specific loading, release, and biological validation are available. This study examines the reservoir-channel architecture of the previously characterized KTD/KTM Ti-6Al-4V capsule platform and evaluates its effect on diffusion-dominated concentration redistribution in a preliminary finite-element model. Micro-computed tomography (micro-CT) was used for qualitative characterization of the as-fabricated internal architecture, whereas the representative computational geometry was defined from the capsule computer-aided design (CAD) concept and previously reported dimensions. Transport of a nominal, fully dissolved species was modeled in COMSOL Multiphysics 5.2 using Fickian diffusion with a prescribed effective diffusion coefficient (

Indexed as

additive manufacturingcomputer-aided designdiffusiondirect metal laser sinteringfinite-element modelingimplantable drug-delivery platformmicro-computed tomographyreservoir–channel architectureTi-6Al-4V

Identifiers

PMID42738194

DOI10.3390/ma19173758

PMCPMC13567317

What OpenQuestion holds

Textmetadata

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.