Graded Mulberry Leaf Supplementation Shapes Gut Microbiota, Reprograms Intestinal Metabolism, and Maintains Intestinal Chemical-Immune Barrier Homeostasis in Amur Sturgeon: A Multi-Omics Study.

Wanwan Zhu, Nan Zhang, Xuekai Wang, Yi Xiong, Yongsheng Wang, Fuyu Yang

Abstract read

In one paragraph

Article in Biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wanwan ZhuDepartment of Grassland Science, College of Animal Science, Guizhou University, Guiyang 550025, China.

Nan ZhangDepartment of Grassland Science, College of Animal Science, Guizhou University, Guiyang 550025, China.

Xuekai WangCollege of Grassland Science and Technology, China Agricultural University, Beijing 100193, China.ORCID 0000-0002-8072-0467

Yi XiongFrontier Technology Research Institute of China Agricultural University in Shenzhen, Shenzhen 518000, China.ORCID 0000-0002-7133-1558

Yongsheng WangShenzhen Branch, Guangdong Laboratory of Lingnan Modern Agriculture, Key Laboratory of Livestock and Poultry Multi-Omics of MARA, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen 518000, China.

Fuyu YangDepartment of Grassland Science, College of Animal Science, Guizhou University, Guiyang 550025, China.

Funding

National Key Research and Development Program of China 2022YFD1300900Shenzhen Major Science and Technology Special Project KJZD20240903103306009

6 · The paper itself

Abstract

Mulberry leaf contains abundant phytochemicals with antioxidant and immunomodulatory activities. However, systematic insight into its dose-dependent regulatory effects on the intestinal health of Amur sturgeon remains limited. In the present study, multi-omics approaches, including 16S rRNA gene sequencing, untargeted metabolomics, transcriptomics, together with RT-qPCR, were applied to investigate graded dietary mulberry leaf supplementation in

Indexed as

Amur sturgeon (Acipenser schrenckii)gut microbiotaintestinal barrier homeostasismetabolomicsmulberry leaftranscriptomics

Identifiers

PMID42737988

DOI10.3390/biology15171556

PMCPMC13564912

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.