Evidence map›Paper›PMID 42737764›Full record

ArticleInternational journal of molecular sciences2026

Enteral Nutrition Is Associated with a Distinct Gut Microbiome Composition and Fermentation Capacity Profile After Acute Colonic Injury in Rats.

Samat Kozhakhmetov, Elizaveta Vinogradova, Shynggys Sergazy, Laura Chulenbayeva, Alibek Kossumov, Artur Kovenskiy, Nurislam Mukhanbetzhanov, Gulnazym Ospankulova, Saule Saduakhasova, Dina Khamitova and 6 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Samat KozhakhmetovLaboratory of Microbiome, Center for Life Sciences, National Laboratory Astana, Nazarbayev University, 53 Kabanbay Batyr Ave., Block S1, Astana Z05H0P9, Kazakhstan.ORCID 0000-0001-9668-0327
Elizaveta VinogradovaLaboratory of Microbiome, Center for Life Sciences, National Laboratory Astana, Nazarbayev University, 53 Kabanbay Batyr Ave., Block S1, Astana Z05H0P9, Kazakhstan.ORCID 0009-0003-1845-2726
Shynggys SergazyVictus Pharm, Astana Z19Y9B3, Kazakhstan.ORCID 0000-0002-6030-620X
Laura ChulenbayevaLaboratory of Microbiome, Center for Life Sciences, National Laboratory Astana, Nazarbayev University, 53 Kabanbay Batyr Ave., Block S1, Astana Z05H0P9, Kazakhstan.ORCID 0000-0002-8691-9485
Alibek KossumovLaboratory of Microbiome, Center for Life Sciences, National Laboratory Astana, Nazarbayev University, 53 Kabanbay Batyr Ave., Block S1, Astana Z05H0P9, Kazakhstan.ORCID 0000-0001-7827-6697
Artur KovenskiyLaboratory of Microbiome, Center for Life Sciences, National Laboratory Astana, Nazarbayev University, 53 Kabanbay Batyr Ave., Block S1, Astana Z05H0P9, Kazakhstan.ORCID 0009-0001-5608-2469
Nurislam MukhanbetzhanovLaboratory of Microbiome, Center for Life Sciences, National Laboratory Astana, Nazarbayev University, 53 Kabanbay Batyr Ave., Block S1, Astana Z05H0P9, Kazakhstan.
Gulnazym OspankulovaDepartment of Food Technology and Processing Products, Technical Faculty, Saken Seifullin Kazakh Agrotechnical University, Zhenis Avenue, 62, Astana Z11F9K5, Kazakhstan.ORCID 0000-0002-6043-4658
Saule SaduakhasovaDepartment of Food Technology and Processing Products, Technical Faculty, Saken Seifullin Kazakh Agrotechnical University, Zhenis Avenue, 62, Astana Z11F9K5, Kazakhstan.ORCID 0000-0002-9483-5732
Dina KhamitovaRegional Technological Park QazAgroOrganic LLP, Saken Seifullin Kazakh Agrotechnical University, Zhenis 62b, Astana Z11F9K5, Kazakhstan.
Svetlana KamanovaDepartment of Food Technology and Processing Products, Technical Faculty, Saken Seifullin Kazakh Agrotechnical University, Zhenis Avenue, 62, Astana Z11F9K5, Kazakhstan.
Dana ToimbayevaDepartment of Food Technology and Processing Products, Technical Faculty, Saken Seifullin Kazakh Agrotechnical University, Zhenis Avenue, 62, Astana Z11F9K5, Kazakhstan.
Bakhyt ShaimenovaDepartment of Food Technology and Processing Products, Technical Faculty, Saken Seifullin Kazakh Agrotechnical University, Zhenis Avenue, 62, Astana Z11F9K5, Kazakhstan.ORCID 0000-0001-5472-036X
Begzhan KalemsharivDepartment of Food Technology and Processing Products, Technical Faculty, Saken Seifullin Kazakh Agrotechnical University, Zhenis Avenue, 62, Astana Z11F9K5, Kazakhstan.ORCID 0000-0002-8036-9718
Daulet AitmukhanbetovRegional Technological Park QazAgroOrganic LLP, Saken Seifullin Kazakh Agrotechnical University, Zhenis 62b, Astana Z11F9K5, Kazakhstan.ORCID 0000-0002-8178-3080
Almagul KushugulovaLaboratory of Microbiome, Center for Life Sciences, National Laboratory Astana, Nazarbayev University, 53 Kabanbay Batyr Ave., Block S1, Astana Z05H0P9, Kazakhstan.ORCID 0000-0001-9479-0899

Funding

Ministry of Agriculture of the Republic of Kazakhstan BR22883587
6 · The paper itself

Abstract

Enteral nutrition (EN) is known to promote mucosal healing in inflammatory bowel disease, and multi-omics data suggest that the gut microbiome mediates its therapeutic effects. However, the impact of EN and its components on the gut community during recovery from acute epithelial injury remains incompletely understood. We used whole-genome metagenomic sequencing to investigate the effect of an EN formula based on extruded amaranth flour and pea protein on the gut microbiome in a dextran sulfate sodium (DSS) rat model of acute colonic injury. Three groups were compared, as follows: an unchallenged control (

Indexed as

ColitisColonEnteral NutritionFermentationGastrointestinal MicrobiomeAnimalsDextran SulfateDisease Models, AnimalMaleMetagenomicsRatsRats, Sprague-DawleyDextran Sulfateacute colonic injurydextran sulfate sodium (DSS)enteral nutritiongut microbiomelactateLactobacillalesmetagenomic next-generation sequencing (mNGS)microbiome functional profilingrats

Identifiers

PMID42737764
PMCPMC13566366

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.