Evidence map›Paper›PMID 42737762›Full record

ArticleInternational journal of molecular sciences2026

Mixed-Culture Fermentation of Coffee Pulp Induces Metabolomic Changes and Enhances Multi-Target Bioactivity Relevant to Androgenetic Alopecia.

Anurak Muangsanguan, Warintorn Ruksiriwanich, Niphawan Panti, Kasirawat Sawangrat, Pattarapa Pummara, Pornchai Rachtanapun, Korawan Sringarm, Sarana Rose Sommano, Sucheewin Krobthong, Chaiwat Arjin and 2 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Anurak MuangsanguanDepartment of Pharmaceutical Sciences, Faculty of Pharmacy, Chiang Mai University, Chiang Mai 50200, Thailand.ORCID 0000-0001-8590-169X
Warintorn RuksiriwanichDepartment of Pharmaceutical Sciences, Faculty of Pharmacy, Chiang Mai University, Chiang Mai 50200, Thailand.ORCID 0000-0002-3940-6441
Niphawan PantiCluster of Agro Bio-Circular-Green Industry (Agro BCG), Chiang Mai University, Chiang Mai 50200, Thailand.
Kasirawat SawangratDepartment of Pharmaceutical Sciences, Faculty of Pharmacy, Chiang Mai University, Chiang Mai 50200, Thailand.ORCID 0000-0002-0936-1588
Pattarapa PummaraFaculty of Agro-Industry, Chiang Mai University, Chiang Mai 50100, Thailand.
Pornchai RachtanapunCluster of Agro Bio-Circular-Green Industry (Agro BCG), Chiang Mai University, Chiang Mai 50200, Thailand.ORCID 0000-0001-8157-4433
Korawan SringarmCluster of Valorization and Bio-Green Transformation for Translation Research Innovation of Raw Materials and Products, Chiang Mai University, Chiang Mai 50200, Thailand.ORCID 0000-0003-0089-8183
Sarana Rose SommanoCluster of Valorization and Bio-Green Transformation for Translation Research Innovation of Raw Materials and Products, Chiang Mai University, Chiang Mai 50200, Thailand.ORCID 0000-0001-7356-2598
Sucheewin KrobthongCenter of Excellence in Natural Products Chemistry (CENP), Department of Chemistry, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand.ORCID 0000-0003-4428-4140
Chaiwat ArjinDepartment of Animal and Aquatic Sciences, Faculty of Agriculture, Chiang Mai University, Chiang Mai 50200, Thailand.ORCID 0000-0001-6297-2890
Apinya SatsookOffice of Research Administration, Chiang Mai University, Chiang Mai 50200, Thailand.ORCID 0000-0003-3922-4047
Juan Manuel CastagniniResearch Group in Innovative Technologies for Sustainable Food (ALISOST), Department of Preventive Medicine and Public Health, Food Science, Toxicology and Forensic Medicine, Faculty of Pharmacy, Universitat de València, Avenida Vicent Andrés Estellés s/n, 46100 Burjassot, Spain.ORCID 0000-0002-3659-3640

Funding

Chiang Mai University and the Thailand Research Fund (TRF) through the Research Team Promo-tion Grant (RTA) and the Senior Research Scholar N42A671052Thailand Science Research and Innovation (TSRI) FRB690042/0162The Fundamental Fund 2026, Chiang Mai University Project Number 214522
6 · The paper itself

Abstract

Androgenetic alopecia (AGA), the most common form of hair loss, is driven by dihydrotestosterone-mediated follicular miniaturization, oxidative stress, and perifollicular inflammation, requiring multi-target intervention. Coffee pulp is an abundant coffee-processing by-product and a potential source of value-added bioactives relevant to AGA. This study investigated whether fermentation with

Indexed as

AlopeciaCoffeeFermentationMetabolomeCell ProliferationFibroblastsHair FollicleHumansMetabolomicsOxidative StressReactive Oxygen SpeciesSaccharomyces cerevisiaeCoffeeReactive Oxygen Species5α-reductaseandrogenetic alopeciaco-culture fermentationcoffee pulphair growth signaling

Identifiers

PMID42737762
PMCPMC13565882

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.