ArticleInternational journal of molecular sciences2026
Profiling Fecal Microbiome and Metabolites in a Feline Infectious Peritonitis Virus Challenge Model in Kittens: A Pilot Discovery Study.
Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
Abstract
Feline infectious peritonitis (FIP), caused by FIPV, is a highly fatal disease. The coordinated shifts in gut microbiota, metabolome, and their interactions following FIPV infection remain poorly understood. In this pilot discovery work, we established an oral FIPV DF-2 challenge model in kittens, which reproduced typical FIP phenotypes confirmed by clinical scores and pathology for exploratory multi-omics profiling. Using V3-V4 16S rRNA sequencing on Illumina PE300 and UHPLC-MS-based untargeted metabolomics, combined with LEfSe, OPLS-DA, and Pearson correlation, we preliminarily characterized fecal microbial and metabolic alterations associated with FIP onset in this exploratory animal model. FIP-affected kittens exhibited reduced abundances of
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.