Evidence map›Paper›PMID 42737720›Full record

ArticleInternational journal of molecular sciences2026

OX40 (TNFRSF4) Tracks Immune Infiltration in Small Cell Lung Cancer and Shows a Cohort-Specific, Non-Replicated Association with the POU2F3/SCLC-P Subtype: A Multi-Source In Silico Analysis.

Mehmet Turan Özer, Faruk Recep Özalp

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Mehmet Turan ÖzerDepartment of Internal Medicine, Osmaniye Training and Research Hospital, 80010 Osmaniye, Türkiye.ORCID 0000-0002-1316-0981
Faruk Recep ÖzalpDepartment of Medical Oncology, Faculty of Medicine, Dokuz Eylül University, 35340 İzmir, Türkiye.ORCID 0000-0002-2863-3243

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

OX40 (TNFRSF4) is a costimulatory T-cell receptor and OX40 agonists are in clinical development, yet its role in small cell lung cancer (SCLC) is still to be characterised. We analysed the discovery cohort (

Indexed as

Lung NeoplasmsReceptors, OX40Small Cell Lung CarcinomaTranscription Factor Brn-3BCell Line, TumorCohort StudiesComputer SimulationHumansReceptors, OX40TNFRSF4 protein, humanTranscription Factor Brn-3Bbiomarker hypothesisimmune infiltrationin silico analysismolecular subtypeOX40POU2F3SCLC-Psmall cell lung cancerTNFRSF4tumour immune microenvironment

Identifiers

PMID42737720
PMCPMC13566540

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.