Evidence map›Paper›PMID 42737706›Full record

ArticleInternational journal of molecular sciences2026

MicroRNA Expression Profiles Before and After Neoadjuvant Chemotherapy in Breast Cancer: Correlations with Molecular Subtypes, Pathological Response, and Clinical Timing-A Pilot Translational Study.

Isabela Anda Komporaly, Adelina Silvana Gheorghe, Elena Adriana Iovănescu, Bogdan Georgescu, Dana Lucia Stănculeanu

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Isabela Anda KomporalyDepartment of Oncology, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Adelina Silvana GheorgheDepartment of Medical Oncology I, "Prof. Dr. Alexandru Trestioreanu" Institute of Oncology, 022328 Bucharest, Romania.ORCID 0000-0003-3589-799X
Elena Adriana IovănescuDepartment of Oncology, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Bogdan GeorgescuDepartment of Oncology, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Dana Lucia StănculeanuDepartment of Oncology, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neoadjuvant chemotherapy (NAC) is the standard of care for locally advanced breast cancer, yet the molecular predictors of pathological response remain incompletely defined, particularly regarding microRNA (miRNA) dynamics. We investigated paired pre- and post-NAC miRNA expression profiles in relation to molecular subtype, residual cancer burden (RCB), and clinical timing parameters. Seven patients with invasive breast cancer (Luminal A

Indexed as

Breast NeoplasmsGene Expression Regulation, NeoplasticMicroRNAsNeoadjuvant TherapyAdultBiomarkers, TumorFemaleGene Expression ProfilingHumansMiddle AgedPilot ProjectsBiomarkers, TumorMicroRNAsbiomarkersbreast cancermicroRNAmolecular subtypesneoadjuvant chemotherapypathological complete responseresidual cancer burdensmall-RNA sequencingtranslational oncology

Identifiers

PMID42737706
PMCPMC13566632

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.