ArticleInternational journal of molecular sciences2026
6PPD and 6PPD-Q Induce Mitochondrial Dysfunction in
Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
N-(1,3-dimethylbutyl)-N'phenyl-p-phenylenediamine, more commonly known as 6PPD, is a tire antiozonant used to prevent rubber oxidation and degradation. When 6PPD reacts with ozone, it becomes 6PPD-Quinone (6PPD-Q). Stormwater road runoff facilitates the transport of phenylenediamines (PPDs) into the environment. In recent years, 6PPD-Q has been identified as an acute environmental toxicant causing major disruptions to aquatic life. To aid in the growing body of knowledge on the mechanism of action of PPD and potentially support environmental regulations, this study aims to elucidate the toxic effects of 6PPD and 6PPD-Q in
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