Structural Features of DNA in TATA-Containing and TATA-Less Core Promoters of RNA Polymerase II Differ.

Ekaterina A Savina, Olga D Soldatenkova, Anastasia A Anashkina, Irina A Il'icheva

Abstract read

In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Ekaterina A SavinaEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, Vavilova 32, Moscow 119991, Russia.ORCID 0009-0004-9874-8873

Olga D SoldatenkovaDepartment of Information and Internet Technologies, Institute of Digital Biodesign and Artificial Intelligence in Medicine, Sechenov University, 8-2 Trubetskaya Str., Moscow 119991, Russia.

Anastasia A AnashkinaEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, Vavilova 32, Moscow 119991, Russia.ORCID 0000-0003-1763-300X

Irina A Il'ichevaEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, Vavilova 32, Moscow 119991, Russia.ORCID 0000-0002-8172-243X

Funding

Program of Fundamental Research in the Russian Federation for the 2021-2030 project No. 124031500019-8

6 · The paper itself

Abstract

Nucleotide motifs in the core promoters of eukaryotic protein-coding genes transcribed by RNA polymerase II (Pol II) play an important role in the transcription process. We analyzed the role of an octanucleotide located in the TATA box position. Depending on whether this octanucleotide can form a complex with the TATA-binding protein (TBP), the promoter is classified as either TATA-containing or TATA-less. We analyzed the differences in the primary and spatial structures, as well as their dynamics, in TATA-containing and TATA-less promoters of mammals and plants. We divided the complete promoter sets of six organisms (

Indexed as

DNAPromoter Regions, GeneticRNA Polymerase IITATA BoxAnimalsHumansNucleic Acid ConformationTATA-Box Binding ProteinTranscription, GeneticDNARNA Polymerase IITATA-Box Binding Proteincore promoter DNA local structureDNase I cleavageeukaryotesTATA boxTATA-lesstranscription apparatusultrasonic cleavage

Identifiers

PMID42737632

DOI10.3390/ijms27177735

PMCPMC13566119

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.